Sterically shielded pyrrolidine nitroxides with 3-(4,5-dicarboxy-1H-1,2,3-triazol-1-yl)propyl substituent

Sterically shielded pyrrolidine nitroxides with 3-(4,5-dicarboxy-1H-1,2,3-triazol-1-yl)propyl substituent Full article

Journal

Russian Chemical Bulletin
ISSN: 1066-5285 , E-ISSN: 1573-9171

Output data

Year: 2023, Volume: 72, Number: 7, Pages: 1569-1575 Pages count : 7 DOI: 10.1007/s11172-023-3935-6

Tags

nitrones nitroxides Grignard reagents pyrrolidine reduction kinetics

Authors

Trakhinina S.Yu. ^1,2 , Taratayko A.I. ¹ , Glazachev Yu.I. ³ , Kirilyuk I.A. ¹

Affiliations

1	N. N. Vorozhtsov Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, 9 prosp. Akad. Lavrent´eva, 630090 Novosibirsk, Russian Federation
2	Novosibirsk State University, 1 ul. Pirogova, 630090 Novosibirsk, Russian Federation
3	Voevodsky Institute of Chemical Kinetics and Combustion, Siberian Branch of the Russian Academy of Sciences, 3 ul. Institutskaya, 630090 Novosibirsk, Russian Federation

Funding (1)

Российский Научный Фонд

21-73-00281

Water-soluble spin probes were obtained from reduction-resistant sterically shielded pyrrolidine nitroxides by forming a 4,5-dicarboxy-1H-1,2,3-triazole fragment in the side chain by the Huisgen reaction of the azido group with acetylenedicarboxylic acid ester followed by hydrolysis. For the synthesized radicals, the reduction rate constants by ascorbate and the partition coefficient in an octanol—water system were determined.

Trakhinina S.Y. , Taratayko A.I. , Glazachev Y.I. , Kirilyuk I.A.
Sterically shielded pyrrolidine nitroxides with 3-(4,5-dicarboxy-1H-1,2,3-triazol-1-yl)propyl substituent
Russian Chemical Bulletin. 2023. V.72. N7. P.1569-1575. DOI: 10.1007/s11172-023-3935-6 WOS РИНЦ

Трахинина С.Ю. , Таратайко А.И. , Глазачев Ю.И. , Кирилюк И.А.
Стерически затрудненные нитроксильные радикалы пирролидинового ряда с 3-(4,5-дикарбокси-1H-1,2,3-триазол-1-ил)пропильным заместителем
Известия Академии наук. Серия химическая.(RUSS CHEM B+). 2023. Т.72. №7. С.1569-1575. РИНЦ

Submitted:	Dec 19, 2022
Accepted:	Jan 25, 2023
Published online:	Aug 2, 2023

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