Synthesis of spin-labeled amides of 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (trolox)

Synthesis of spin-labeled amides of 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (trolox) Full article

Journal

Chemistry of Natural Compounds
ISSN: 0009-3130 , E-ISSN: 1573-8388

Output data

Year: 2013, Volume: 49, Number: 2, Pages: 253-257 Pages count : DOI: 10.1007/s10600-013-0574-4

Tags

trolox; nitroxyl radicals; spin-labeled compounds

Authors

Yushkova Yu V. ¹ , Chernyak E. I. ¹ , Polienko Yu F. ¹ , Gatilov Yu V. ¹ , Morozov S. V. ¹ , Grigor'ev I. A. ¹

Affiliations

1	(Данные Web of science) Russian Acad Sci, NN Vorozhtsov Novosibirsk Inst Organ Chem, Siberian Branch, Novosibirsk 630090, Russia

Reaction of 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (trolox) with 4-amino-2,2,6,6-tetramethylpiperidine-1-oxyl, 3-amino-2,2,5,5-tetramethylpyrrolidine-1-oxyl, and 3-aminomethyl-2,2,5,5-tetramethylpyrrolidine-1-oxyl synthesized the corresponding spin-labeled amides. The synthesized compounds exhibited antioxidant potential and were promising for application in biomedical studies using magnetic-resonance imaging (MRI).

Yushkova Y.V. , Chernyak E.I. , Polienko Y.F. , Gatilov Y.V. , Morozov S.V. , Grigor'ev I.A.
Synthesis of spin-labeled amides of 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (trolox)
Chemistry of Natural Compounds. 2013. V.49. N2. P.253-257. DOI: 10.1007/s10600-013-0574-4 WOS Scopus РИНЦ

Published print:	May 1, 2013
Published online:	Jun 15, 2013

Web of science	WOS:000320770600013
Scopus	2-s2.0-84879797981
Elibrary	20439089
OpenAlex	W2046657979