Synthesis and anxiolytic activity of 2-aminoadamantane derivatives containing monoterpene fragments

Synthesis and anxiolytic activity of 2-aminoadamantane derivatives containing monoterpene fragments Full article

Journal

Pharmaceutical Chemistry Journal
ISSN: 0091-150X , E-ISSN: 1573-9031

Output data

Year: 2012, Volume: 46, Number: 5, Pages: 263-265 Pages count : DOI: 10.1007/s11094-012-0775-3

Tags

2-aminoadamantane; citral; (-)-myrtenal; terpenoids; anxiolytic activity

Authors

Kapitsa I. G. ¹ , Suslov E. V. ² , Teplov G. V. ² , Korchagina D. V. ² , Komarova N. I. ² , Volcho K. P. ² , Voronina T. A. ¹ , Shevela A. I. ³ , Salakhutdinov N. F. ²

Affiliations

1	(Данные Web of science) Russian Acad Med Sci, Zakusov Inst Pharmacol, Moscow 125315, Russia
2	(Данные Web of science) Russian Acad Sci, Vorozhtsov Inst Organ Chem, Siberian Branch, Irkutsk 664003, Russia
3	(Данные Web of science) Russian Acad Sci, Inst Chem Biol & Fundamental Med, Siberian Branch, Novosibirsk 630090, Russia

Two new amines were synthesized from 2-aminoadamantane and the available monoterpenoid aldehydes citral and (-)-myrtenal. It was established that the synthesized amines possessed anxiolytic activity.

Kapitsa I.G. , Suslov E.V. , Teplov G.V. , Korchagina D.V. , Komarova N.I. , Volcho K.P. , Voronina T.A. , Shevela A.I. , Salakhutdinov N.F.
Synthesis and anxiolytic activity of 2-aminoadamantane derivatives containing monoterpene fragments
Pharmaceutical Chemistry Journal. 2012. V.46. N5. P.263-265. DOI: 10.1007/s11094-012-0775-3 WOS Scopus РИНЦ

Published print:	Aug 1, 2012
Published online:	Sep 11, 2012

Web of science	WOS:000308858000001
Scopus	2-s2.0-85027947414
Elibrary	41782608
OpenAlex	W2062885677