Phototransformation products of the alkaloid lappaconitine: Multinuclear NMR study

Phototransformation products of the alkaloid lappaconitine: Multinuclear NMR study Full article

Journal

Journal of Photochemistry and Photobiology A: Chemistry
ISSN: 1010-6030

Output data

Year: 2008, Volume: 197, Number: 2-3, Pages: 290-294 Pages count : DOI: 10.1016/j.jphotochem.2008.01.006

Tags

lappaconitine; phototransformation; N-acetylanthranilic acid; NMR

Authors

Polyakov Nikolay E. , Leshina Tatyana V. , Tkachev Alexey V. , Nikitina Irina A. , Pankrushina Natalia A.

Affiliations

1	(Данные Web of science) Russian Acad Sci, Inst Chem Kinet & Combust, Novosibirsk 630090, Russia
2	(Данные Web of science) Novosibirsk Organ Chem Inst, Novosibirsk 630090, Russia
3	(Данные Web of science) NSU, Res & Educ Ctr Mol Design & Ecologically Safe Tec, Novosibirsk 630090, Russia

The NMR technique has been applied to characterize the phototransformation products of the natural alkaloid lappaconitine. It was demonstrated that the photolysis of lappaconitine 1 results in cleavage of the ester bond with elimination of N-acetylanthranilic acid. The final reaction product was found to be an immonium salt 4 of N-acetylanthranilic acid and enamine 3. An equilibrium between the imine cation and the enamine 3 was detected. (c) 2008 Elsevier B.V. All rights reserved.

Polyakov N.E. , Leshina T.V. , Tkachev A.V. , Nikitina I.A. , Pankrushina N.A.
Phototransformation products of the alkaloid lappaconitine: Multinuclear NMR study
Journal of Photochemistry and Photobiology A: Chemistry. 2008. V.197. N2-3. P.290-294. DOI: 10.1016/j.jphotochem.2008.01.006 WOS Scopus РИНЦ

Published print:

Jun 1, 2008

Web of science	WOS:000256780100022
Scopus	2-s2.0-43049134858
Elibrary	22149105
OpenAlex	W1977376483