Synthesis of benzo[c][1,7]naphthyridine derivatives

Synthesis of benzo[c][1,7]naphthyridine derivatives Full article

Journal

Chemistry of Heterocyclic Compounds
ISSN: 0009-3122 , E-ISSN: 1573-8353

Output data

Year: 2019, Volume: 55, Number: 11, Pages: 1080-1086 Pages count : 7 DOI: 10.1007/s10593-019-02581-8

Tags

benzo[c][1,7]naphthyridine; alkylation; electrophilic substitution; nucleophilic substitution; oxidation; reactivity

Authors

Shatsauskas Anton L. ¹ , Saibulina Elina R. ² , Gatilov Yurii V. ^3,4 , Kostyuchenko Anastasia S. ^1,2 , Fisyuk Alexander S. ¹

Affiliations

1	(Данные Web of science) Omsk State Tech Univ, 11 Mira Ave, Omsk 644050, Russia
2	(Данные Web of science) Dostoevsky Omsk State Univ, 55a Mira Ave, Omsk 644077, Russia
3	(Данные Web of science) Russian Acad Sci, Siberian Branch, NN Vorozhtsov Novosibirsk Inst Organ Chem, 9 Akad Lavrentieva Ave, Novosibirsk 630090, Russia
4	(Данные Web of science) Novosibirsk State Univ, 2 Pirogova St, Novosibirsk 630090, Russia

Reactivity of 2-methyl-6-phenylbenzo[c][1,7]naphthyridine in alkylation, oxidation, and electrophilic substitution reactions has been studied. The reaction of 2-methyl-6-phenylbenzo[c][1,7]naphthyridines with POCl3 yielded the previously unknown 4-chloro-2-methyl6-phenylbenzo[c][1,7]naphthyridine. Its dehalogenation and substitution of halogen by nitrogen and sulfur nucleophiles were studied.

Shatsauskas A.L. , Saibulina E.R. , Gatilov Y.V. , Kostyuchenko A.S. , Fisyuk A.S.
Synthesis of benzo[c][1,7]naphthyridine derivatives
Chemistry of Heterocyclic Compounds. 2019. V.55. N11. P.1080-1086. DOI: 10.1007/s10593-019-02581-8 WOS Scopus РИНЦ

Published print:	Nov 1, 2019
Published online:	Nov 25, 2019

Web of science	WOS:000510838100007
Scopus	2-s2.0-85076018018
Elibrary	43216573
OpenAlex	W2990499633