Synthesis of 5-nitro-3,4-dihydropyrimidin-2(1H)-ones catalyzed by metal salts. Retro-Henry reaction with formation of N,N '-disubstituted ureas

Synthesis of 5-nitro-3,4-dihydropyrimidin-2(1H)-ones catalyzed by metal salts. Retro-Henry reaction with formation of N,N '-disubstituted ureas Full article

Journal

Russian Journal of Organic Chemistry
ISSN: 1070-4280 , E-ISSN: 1608-3393

Output data

Year: 2007, Volume: 43, Number: 1, Pages: 90-95 Pages count : 6 DOI: 10.1134/S1070428007010113

Authors

Sedova V.F. ¹ , Krivopalov V.P. ¹ , Shkurko O.P. ¹

Affiliations

1	(Данные Web of science) Russian Acad Sci, Siberian Div, Vorozhtsov Novosibirsk Inst Organ Chem, Novosibirsk 630090, Russia

Three-component condensation of alpha-nitroacetophenone with aromatic aldehydes and urea in the presence of iron(III), cobalt(II), nickel(II), and copper(II) salts as catalyst led to the formation of 4,6-diaryl-5-nitro-3,4-dihydropyrimidin-2(1H)-ones and N-benzoyl-N'-(1-aryl-2-nitroethyl)ureas. The latter were formed as a result of retro-nitroaldol (retro-Henry) reaction of intermediate 4,6-diaryl-6-hydroxy-5-nitro-3,4,5,6-tetra-hydropyrimidin-2(1H)-ones.

Sedova V.F. , Krivopalov V.P. , Shkurko O.P.
Synthesis of 5-nitro-3,4-dihydropyrimidin-2(1H)-ones catalyzed by metal salts. Retro-Henry reaction with formation of N,N '-disubstituted ureas
Russian Journal of Organic Chemistry. 2007. V.43. N1. P.90-95. DOI: 10.1134/S1070428007010113 WOS Scopus РИНЦ

Седова В.Ф. , Кривопалов В.П. , Шкурко О.П.
Синтез 5-нитро-3,4-дигидропиримидин-2(1h)-онов, катализируемый солями металлов. ретро-реакция с образованием n1,n3-дизамещенных мочевин
Журнал органической химии (RUSS J ORG CHEM+). 2007. Т.43. №1. С.87-91. РИНЦ

Published print:

Jan 1, 2007

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