Synthesis of functional 2-substituted 4-phenyl-9H-pyrimido[4,5-b]indoles Full article
| Journal |
Russian Chemical Bulletin
ISSN: 1066-5285 , E-ISSN: 1573-9171 |
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| Output data | Year: 2002, Volume: 51, Number: 11, Pages: 2129-2133 Pages count : DOI: 10.1023/A:1021688616234 | ||
| Tags | 2-oxo-4-phenyl-2,3-dihydro-9H-pyrimido[4,5-b]indole; 2-substituted 4-phenyl-9H-pyrimido[4,5-b]indoles; diazotization; nucleophilic substitution; catalytic hydrogenation | ||
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Abstract:
A method was developed for the synthesis of 2-oxo-4-phenyl-2,3-dihydro-9H-pyrimido[4,5-b]indole as well as of 2-chloro- and 2-nitramino-4-phenylpyrimido[4,5-b]indoles. The replacement of the chlorine atom in 2-chloropyrimidoindole gave rise to a number of its functional derivatives (morpholino, azido, and cyano). The reaction of 2-chloro-substituted pyrimidoindole with hydrazine hydrate and catalytic hydrogenation of 2-nitraminopyrimidoindole were studied.
Cite:
Borovik V.
, Shkurko O.
Synthesis of functional 2-substituted 4-phenyl-9H-pyrimido[4,5-b]indoles
Russian Chemical Bulletin. 2002. V.51. N11. P.2129-2133. DOI: 10.1023/A:1021688616234 WOS Scopus РИНЦ
Synthesis of functional 2-substituted 4-phenyl-9H-pyrimido[4,5-b]indoles
Russian Chemical Bulletin. 2002. V.51. N11. P.2129-2133. DOI: 10.1023/A:1021688616234 WOS Scopus РИНЦ
Identifiers:
| Web of science | WOS:000180430300024 |
| Scopus | 2-s2.0-0036920893 |
| Elibrary | 13407111 |
| OpenAlex | W2950142479 |