Alkyl-substituted 1,1'-Dihydroxy-2,2'bimidazoles: Reactions with Methyl Iodide and Trimethyl Phosphite

Alkyl-substituted 1,1'-Dihydroxy-2,2'bimidazoles: Reactions with Methyl Iodide and Trimethyl Phosphite Full article

Journal

Russian Journal of Organic Chemistry
ISSN: 1070-4280 , E-ISSN: 1608-3393

Output data

Year: 2020, Volume: 56, Number: 2, Pages: 339-342 Pages count : 4 DOI: 10.1134/S107042802001027X

Tags

1; 1'-dihydroxy-2; 2'-biimidazoles; 2; 2'-biimidazoles; methylation; reduction

Authors

Os'kina I.A. ¹ , Tikhonov A.Ya ¹

Affiliations

1	(Данные Web of science) Russian Acad Sci, Vorozhtsov Novosibirsk Inst Organ Chem, Siberian Branch, Novosibirsk 630090, Russia

The alkylation of alkyl-substituted 1,1'-dihydroxy-2,2'-biimidazoles with an equimolar amount of methyl iodide occurs exclusively at the imidazole nitrogen atom, while with a three-fold excess of methyl iodide, both the imidazole nitrogen atom and two hydroxy groups are involved in alkylation. The reaction of 1,1'-dihydroxy-2,2'-biimidazoles with P(OMe)(3) forms the corresponding 2,2'-biimidazoles.

Os'kina I.A. , Tikhonov A.Y.
Alkyl-substituted 1,1'-Dihydroxy-2,2'bimidazoles: Reactions with Methyl Iodide and Trimethyl Phosphite
Russian Journal of Organic Chemistry. 2020. V.56. N2. P.339-342. DOI: 10.1134/S107042802001027X WOS Scopus РИНЦ

Оськина И.А. , Тихонов А.Я.
Алкилзамещенные 1,1-дигидрокси-2,2-бисимидазолы: реакции с иодметаном и триметилфосфитом
Журнал органической химии (RUSS J ORG CHEM+). 2020. Т.56. №2. С.303-306. DOI: 10.31857/S0514749220020214 РИНЦ

Published print:	Feb 1, 2020
Published online:	Apr 24, 2020

Web of science	WOS:000524913900027
Scopus	2-s2.0-85083057776
Elibrary	43270705
OpenAlex	W3015907157