Synthesis of 2-[2-(hydroxyimino)alkyl]-1,2-oxazol-5(2H)-ones

Synthesis of 2-[2-(hydroxyimino)alkyl]-1,2-oxazol-5(2H)-ones Full article

Journal

Chemistry of Heterocyclic Compounds
ISSN: 0009-3122 , E-ISSN: 1573-8353

Output data

Year: 2020, Volume: 56, Number: 2, Pages: 208-212 Pages count : 5 DOI: 10.1007/s10593-020-02645-0

Tags

ethyl acetoacetate; hydroxyamino oximes; imidazo[1; 2-b][1; 2]oxazolones; 1; 2-oxazol-5(2H)-ones; X-ray structural analysis

Authors

Nikolaenkova Elena B. ¹ , Bagryanskaya Irina Yu. ¹ , Tikhonov Alexsei Ya. ¹

Affiliations

1	(Данные Web of science) Russian Acad Sci, Siberian Branch, NN Vorozhtsov Novosibirsk Inst Organ Chem, 9 Akad Lavrentieva Ave, Novosibirsk 630090, Russia

The reaction of alpha-hydroxyamino oximes with ethyl acetoacetate and ethyl alpha-methylacetoacetate yields 2-[2-(hydroxyimino)alkyl]-1,2-oxazol-5(2H)-ones. In the reaction of alkylaromatic alpha-hydroxyamino oximes with ethyl acetoacetate, the intermediate imidazo[1,2-b]-[1,2]oxazolones were isolated, which then convert to the target compounds.

Nikolaenkova E.B. , Bagryanskaya I.Y. , Tikhonov A.Y.
Synthesis of 2-[2-(hydroxyimino)alkyl]-1,2-oxazol-5(2H)-ones
Chemistry of Heterocyclic Compounds. 2020. V.56. N2. P.208-212. DOI: 10.1007/s10593-020-02645-0 WOS Scopus РИНЦ

Published print:	Feb 1, 2020
Published online:	Mar 6, 2020

Web of science	WOS:000527962300011
Scopus	2-s2.0-85081619655
Elibrary	43253724
OpenAlex	W3012468942