Synthesis of 1,2-bis(methoxyamino)cycloalkanes from alicyclic 1,2-bis(hydroxyamines)

Synthesis of 1,2-bis(methoxyamino)cycloalkanes from alicyclic 1,2-bis(hydroxyamines) Full article

Journal

Russian Chemical Bulletin
ISSN: 1066-5285 , E-ISSN: 1573-9171

Output data

Year: 1996, Volume: 45, Number: 4, Pages: 880-884 Pages count : 5 DOI: 10.1007/BF01431317

Tags

1,2-bis(hydroxyamines); 1,2-bis(methoxyamines); 1,2-bis(methoxyamino)cycloalkanes; piperazinediones; cyclic hydroxamic acids; alkylation; hydrolysis

Authors

Mazhukin D.G. ¹ , Khlestkin V.K. ² , Tikhonov A.Ya. ¹ , Volodarsky L.B. ¹

Affiliations

1	Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, 9 prosp. akad. Lavrent'eva, 630090, Novosibirsk, Russian Federation
2	Novosibirsk State University, 2 ul. Pirogova, 630090, Novosibirsk, Russian Federation

Derivatives of 1,4-dihydroxypiperazine-2,3-dione were obtained by reaction of cis-1,2-bis(hydroxyamino)cycloalkanes with diethyl oxalate. Their alkylation with CH2N2 or Mel afforded 1,4-dimethoxypiperazine-2,3-diones. Hydrolysis of the latter gave 1,2-bis(methoxyamino)cycloalkanes.

Mazhukin D.G. , Khlestkin V.K. , Tikhonov A.Y. , Volodarsky L.B.
Synthesis of 1,2-bis(methoxyamino)cycloalkanes from alicyclic 1,2-bis(hydroxyamines)
Russian Chemical Bulletin. 1996. V.45. N4. P.880-884. DOI: 10.1007/BF01431317 WOS Scopus РИНЦ

Published print:	Apr 1, 1996
Published online:	Apr 1, 1996

Web of science	WOS:A1996VB91600026
Scopus	2-s2.0-0030492343
Elibrary	13237162
OpenAlex	W2024213920