2H-Benzimidazole N-oxides: synthesis, chemical properties, and biological activity

2H-Benzimidazole N-oxides: synthesis, chemical properties, and biological activity Full article

Journal

Russian Chemical Bulletin
ISSN: 1066-5285 , E-ISSN: 1573-9171

Output data

Year: 2018, Volume: 67, Number: 11, Pages: 1955-1970 Pages count : DOI: 10.1007/s11172-018-2315-0

Tags

2H-benzimidazole 1; 3-dioxide; 2H-benzimidazole mono-N-oxide; 3H-2; 1; 4-benzoxadiazine 4-oxide; benzofuroxan; "hybrid" compounds; Trypanosoma cruzi

Authors

Chugunova E. A. ¹ , Samsonov V. A. ² , Gazizov A. S. ¹ , Burilov A. R. ¹ , Pudovik M. A. ¹ , Sinyashin O. G. ¹

Affiliations

1	(Данные Web of science) Russian Acad Sci, Kazan Sci Ctr, AE Arbuzov Inst Organ & Phys Chem, 8 Ul Akad Arbuzova, Kazan 420088, Russia
2	(Данные Web of science) Russian Acad Sci, Siberian Branch, NN Vorozhtsov Novosibirsk Inst Organ Chem, 9 Prosp Akad Lavrentieva, Novosibirsk 630090, Russia

The review presents and summarizes comprehensive data starting from 2006 on the synthesis of mono- and di-N-oxides of 2H-benzimidazoles and their chemical properties. Especial attention was paid to the chemical transformations of 2H-benzimidazole 1,3-dioxides upon heating to give 3H-2,1,4-benzoxadiazine 4-oxides and 2H-benzimidazole mono-N-oxides. The biological activity of compounds was covered.

Chugunova E.A. , Samsonov V.A. , Gazizov A.S. , Burilov A.R. , Pudovik M.A. , Sinyashin O.G.
2H-Benzimidazole N-oxides: synthesis, chemical properties, and biological activity
Russian Chemical Bulletin. 2018. V.67. N11. P.1955-1970. DOI: 10.1007/s11172-018-2315-0 WOS Scopus РИНЦ

Чугунова Е.А. , Самсонов В.А. , Газизов А.С. , Бурилов А.Р. , Пудовик М.А. , Синяшин О.Г.
N-оксиды 2h-бензимидазола: синтез, химические свойства и биологическая активность
Известия Академии наук. Серия химическая.(RUSS CHEM B+). 2018. №11. С.1955-1970.. РИНЦ

Published print:	Nov 1, 2018
Published online:	Dec 27, 2018

Web of science	WOS:000454510700002
Scopus	2-s2.0-85059346358
Elibrary	38659390
OpenAlex	W2908012202