Antiulcerogenic activity of borneol derivatives

Antiulcerogenic activity of borneol derivatives Full article

Journal

Russian Chemical Bulletin
ISSN: 1066-5285 , E-ISSN: 1573-9171

Output data

Year: 2018, Volume: 67, Number: 3, Pages: 558-561 Pages count : 4 DOI: 10.1007/s11172-018-2110-y

Tags

borneol derivatives; antiulcerogenic activity

Authors

Borisova M.S. ¹ , Yarovaya O.I. ^1,2 , Semenova M.D. ¹ , Tolstikova T.G. ^1,2 , Salakhutdinov N.F. ^1,2

Affiliations

1	(Данные Web of science) Russian Acad Sci, NN Vorozhtsov Novosibirsk Inst Organ Chem, Siberian Branch, 9 Ul Lavrenteva, Novosibirsk 630090, Russia
2	(Данные Web of science) Novosibirsk State Univ, 2 Ul Pirogova, Novosibirsk 630090, Russia

Antiulcerogenic activity of borneol and its N-heterocyclic esters was investigated using indomethacin-induced gastric ulcer model. A considerable antiulcerogenic effect comparable to that shown by Omeprazole and Famotidine was found for two investigated compounds in the indomethacin-induced gastric ulcer model. Bornyl 2-piperazinoacetate, with a non-substituted piperazine moiety, showed maximum antiulcerogenic activity in the indomethacininduced gastric ulcer model and demonstrated a significant gastroprotective effect in the ethanol-induced gastric ulcer model comparable to the effect of Omeprazole.

Borisova M.S. , Yarovaya O.I. , Semenova M.D. , Tolstikova T.G. , Salakhutdinov N.F.
Antiulcerogenic activity of borneol derivatives
Russian Chemical Bulletin. 2018. V.67. N3. P.558-561. DOI: 10.1007/s11172-018-2110-y WOS Scopus РИНЦ

Борисова М.С. , Яровая О.И. , Семенова М.Д. , Толстикова Т.Г. , Салахутдинов Н.Ф.
Противоязвенная активность производных борнеола
Известия Академии наук. Серия химическая.(RUSS CHEM B+). 2018. №3. С.558-561. РИНЦ

Published print:	Mar 1, 2018
Published online:	Jun 25, 2018

Web of science	WOS:000436260900025
Scopus	2-s2.0-85049339495
Elibrary	35744485
OpenAlex	W2810409164