Stevioside - a new simulator of effect of clathration of pharmacons by glycosides

Stevioside - a new simulator of effect of clathration of pharmacons by glycosides Full article

Journal

Доклады академии наук
ISSN: 0869-5652

Output data

Year: 2005, Volume: 403, Number: 2, Pages: 274-276 Pages count : 3

Authors

Tolstikova T.G. , Bryzgalov A.O. , Sorokina I.V. , Morozova E.A. , Tolstikov S.E. , Al'fonsov A.V. , Tolstikov A.G.

Affiliations

1	(Scopus) Novosibirskij Inst. Organicheskoj Khimii im. N.N. Vorozhtsova SO RAN, Novosibirsk, Russian Federation

Diterpeno glycoside stevioside - producent of Stevia rebaudiana was investigated as pharmacon-clathrating agent, alkaloid lappaconitine was taken as pharmacon. The conducted tests on rats produced one more evidence for the hypothesis, according to which decreasing of therapeutic dose of pharmacons at clathrate formation with glycosides is a specific property of terpenoid glycosides capable of supramolecular structure formation in vivo.

Tolstikova T.G. , Bryzgalov A.O. , Sorokina I.V. , Morozova E.A. , Tolstikov S.E. , Al'fonsov A.V. , Tolstikov A.G.
Stevioside - a new simulator of effect of clathration of pharmacons by glycosides
Доклады академии наук. 2005. V.403. N2. P.274-276. Scopus РИНЦ

Scopus	2-s2.0-27744515672
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