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The effect of betulonic acid and its alanine amide derivatives on rat liver parenchyma repair during postcytostatic period [Эффективность бетулоновой кислоты и ее аланинамидных производных при восстановлении паренхимы печени крыс в постцитостатический период] Full article

Journal Экспериментальная и клиническая фармакология/Eksperimental'naya i Klinicheskaya Farmakologiya
ISSN: 0869-2092
Output data Year: 2005, Volume: 68, Number: 6, Pages: 49-51 Pages count : 3
Authors Grek O.R. 1 , Pozdnyakova S.V. 1 , Nadeev A.P. 1 , Pronin V.S. 1 , Zhukova N.A. 2 , Sorokina I.V. 2 , Volkova E.B. 2 , Tolstikova T.G. 2
Affiliations
1 (Scopus) Pharmacology Department, Novosibirsk State Medical Academy, Krasnyi pr. 52, Novosibirsk, 630091, Russian Federation
2 (Scopus) Vorozhtsov Institute of Organic Chemistry, Siberian Division, Russian Academy of Sciences, pr. Lavrent'eva 9, Novosibirsk, 630090, Russian Federation

Abstract: The effects of betulonic acid, its p-alanine amide derivative, and p-alanine amide derivative of betulonic acid methyl ether on the histologic structure of rat liver have been studied on the model of experimental polychemotherapy in rats. These agents significantly decrease the dystrophic and cytolytic damage of hepatocytes and increase the repair processes in liver parenchyma.
Cite: Grek O.R. , Pozdnyakova S.V. , Nadeev A.P. , Pronin V.S. , Zhukova N.A. , Sorokina I.V. , Volkova E.B. , Tolstikova T.G.
The effect of betulonic acid and its alanine amide derivatives on rat liver parenchyma repair during postcytostatic period [Эффективность бетулоновой кислоты и ее аланинамидных производных при восстановлении паренхимы печени крыс в постцитостатический период]
Экспериментальная и клиническая фармакология/Eksperimental'naya i Klinicheskaya Farmakologiya. 2005. V.68. N6. P.49-51. Scopus РИНЦ
Identifiers:
Scopus 2-s2.0-29544452878
Elibrary 22569458