Reaction of 2,4,6-trialkylpyrimidine 1,3-dioxides with electrophilic reagents

Reaction of 2,4,6-trialkylpyrimidine 1,3-dioxides with electrophilic reagents Full article

Journal

Chemistry of Heterocyclic Compounds
ISSN: 0009-3122 , E-ISSN: 1573-8353

Output data

Year: 1981, Volume: 17, Number: 1, Pages: 89-95 Pages count : DOI: 10.1007/BF00507100

Authors

Tikhonov A. Ya. , Volodarskii L. B. , Vakolova O. A. , Podgornaya M. I.

Affiliations

1	(Scopus) Novosibirsk Institute of Organic Chemistry, Siberian Branch, Academy of Sciences of the USSR, Novosibirsk, 630090, Russian Federation

The nitrosation of 2,4,6-trimethylpyrimidine 1,3-dioxide and the bromination of 2,4,6-trimethyl- and 2-ethyl-4,6-dimethylpyrimidine 1,3-dioxides take place primarily at the methyl groups in the 4 and 6 positions of the heteroring. In the reaction of 2,4,6-trimethylpyrimidine 1,3-dioxide with phosphorus oxychloride chlorine is incorporated in the methyl group in the 2 position of the heteroring, while in the reaction with acetic anhydride an acetoxy group is incorporated in the methyl group in the 2 position and in the 5 position of the heteroring, whereas in the case of tosyl chloride a tosyloxy group is incorporated in the 5 position of the heteroring. © 1981 Plenum Publishing Corporation.

Tikhonov A.Y. , Volodarskii L.B. , Vakolova O.A. , Podgornaya M.I.
Reaction of 2,4,6-trialkylpyrimidine 1,3-dioxides with electrophilic reagents
Chemistry of Heterocyclic Compounds. 1981. V.17. N1. P.89-95. DOI: 10.1007/BF00507100 Scopus РИНЦ

Published print:

Jan 1, 1981

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