Synthesis of new heterocyclic dehydroabietylamine derivatives and their biological activity

Synthesis of new heterocyclic dehydroabietylamine derivatives and their biological activity Full article

Journal

Chemistry of Heterocyclic Compounds
ISSN: 0009-3122 , E-ISSN: 1573-8353

Output data

Year: 2017, Volume: 53, Number: 3, Pages: 364-370 Pages count : 7 DOI: 10.1007/s10593-017-2058-0

Tags

dehydroabietylamine; antibacterial activity; antiviral activity; natural compounds

Authors

Kovaleva Kseniya S. ^1,2 , Yarovaya Olga I. ^1,2 , Shernyukov Andrey V. ¹ , Zarubaev Vladimir V. ³ , Shtro Anna A. ³ , Orshanskaya Yana R. ³ , Salakhutdinov Nariman F. ^1,2

Affiliations

1	(Данные Web of science) Russian Acad Sci, Siberian Branch, NN Vorozhtsov Novosibirsk Inst Organ Chem, 9 Lavrentieva Ave, Novosibirsk 630090, Russia
2	(Данные Web of science) Novosibirsk State Univ, 9 Pirogova St, Novosibirsk 630090, Russia
3	(Данные Web of science) Res Inst Influenza, Dept Chemotherapy, 17 Prof Popova St, St Petersburg 197376, Russia

New derivatives of dehydroabietylamine were obtained by transformation of primary amino group to pyrrolidine, piperidine, azepane, morpholine, isoindoline, and pyrrole heterocycles. The obtained compounds were tested for antiviral activity against influenza A/California/07/09 (H1N1)pdm09 strain, as well as the activity against some types of bacteria and fungi.

Kovaleva K.S. , Yarovaya O.I. , Shernyukov A.V. , Zarubaev V.V. , Shtro A.A. , Orshanskaya Y.R. , Salakhutdinov N.F.
Synthesis of new heterocyclic dehydroabietylamine derivatives and their biological activity
Chemistry of Heterocyclic Compounds. 2017. V.53. N3. P.364-370. DOI: 10.1007/s10593-017-2058-0 WOS Scopus РИНЦ

Published print:	Mar 1, 2017
Published online:	Apr 27, 2017

Web of science	WOS:000400545300016
Scopus	2-s2.0-85018318900
Elibrary	31043195
OpenAlex	W2609423664