Influenza Antiviral Activity of Br-Containing [2R,4R(S),4aR,7R,8aR]-4,7-Dimethyl-2-(Thiophen-2-YL)Octahydro-2H-Chromen-4-Ols Prepared from (-)-Isopulegol

Influenza Antiviral Activity of Br-Containing [2R,4R(S),4aR,7R,8aR]-4,7-Dimethyl-2-(Thiophen-2-YL)Octahydro-2H-Chromen-4-Ols Prepared from (-)-Isopulegol Full article

Journal

Chemistry of Natural Compounds
ISSN: 0009-3130 , E-ISSN: 1573-8388

Output data

Year: 2017, Volume: 53, Number: 2, Pages: 260-264 Pages count : 5 DOI: 10.1007/s10600-017-1966-7

Tags

antiviral activity; clay; heterocyclic compounds; influenza A; monoterpenes; thiophenecarboxaldehyde

Authors

Nazimova E.V. ¹ , Shtro A.A. ² , Anikin V.B. ² , Patrusheva O.S. ¹ , Il'ina I.V. ^1,3 , Korchagina D.V. ¹ , Zarubaev V.V. ² , Volcho K.P. ^1,3 , Salakhutdinov N.F. ^1,3

Affiliations

1	(Данные Web of science) Russian Acad Sci, Siberian Branch, NN Vorozhtsov Novosibirsk Inst Organ Chem, 9 Prosp Akad Lavrenteva, Novosibirsk 630090, Russia
2	(Данные Web of science) MHRF, RII, 15-17 Prof Popov St, St Petersburg 197376, Russia
3	(Данные Web of science) Novosibirsk Natl Res State Univ, 2 Pirogov St, Novosibirsk 630090, Russia

Influenza A (H1N1) antiviral activity of compounds with an octahydro-2H-chromene skeleton that were prepared by reacting the monoterpenoid (-)-isopulegol and thiophenecarboxaldehyde and its derivatives was studied for the first time. The 5-bromothiophene-2-carboxaldehyde derivative exhibited the greatest antiviral activity.

Nazimova E.V. , Shtro A.A. , Anikin V.B. , Patrusheva O.S. , Il'ina I.V. , Korchagina D.V. , Zarubaev V.V. , Volcho K.P. , Salakhutdinov N.F.
Influenza Antiviral Activity of Br-Containing [2R,4R(S),4aR,7R,8aR]-4,7-Dimethyl-2-(Thiophen-2-YL)Octahydro-2H-Chromen-4-Ols Prepared from (-)-Isopulegol
Chemistry of Natural Compounds. 2017. V.53. N2. P.260-264. DOI: 10.1007/s10600-017-1966-7 WOS Scopus РИНЦ

Published print:	Mar 1, 2017
Published online:	Apr 19, 2017

Web of science	WOS:000400195700013
Scopus	2-s2.0-85018495476
Elibrary	31018610
OpenAlex	W2607414692