Synthesis of Novel Labdanoid-Based Macroheterocycles Using Click-Cycloaddition Reaction Protocol

Synthesis of Novel Labdanoid-Based Macroheterocycles Using Click-Cycloaddition Reaction Protocol Full article

Journal

Macroheterocycles
ISSN: 1998-9539

Output data

Year: 2017, Volume: 10, Number: 1, Pages: 117-122 Pages count : 6 DOI: 10.6060/mhc160959s

Tags

Diterpenoids; lamberianic acid; dialkynes; diazides; CuAAC-reaction; macrocycles

Authors

Kharitonov Yurii V. ^1,2 , Shakirov Makhmut M. ¹ , Shults Elvira E. ^1,2

Affiliations

1	(Данные Web of science) Russian Acad Sci, Novosibirsk Inst Organ Chem, Siberian Branch, Novosibirsk 630090, Russia
2	(Данные Web of science) Novosibirsk State Univ, Novosibirsk 630090, Russia

A convenient synthetic method to diterpenoid dialkyne 18-propargyloxy-16-[(prop-2-yn-1-yloxi)methyl]labda-8(17),13,15-triene in the common yield of 34 % from the natural plant diterpenoid lambertianic acid was developed. 1,2,3-Triazolyl containing macroheterocyclic compounds with an integrated diterpenoid fragment have been prepared by CuAAC reaction of the labdanoid dialkyne with organic diazides.

Kharitonov Y.V. , Shakirov M.M. , Shults E.E.
Synthesis of Novel Labdanoid-Based Macroheterocycles Using Click-Cycloaddition Reaction Protocol

Macroheterocycles. 2017. V.10. N1. P.117-122. DOI: 10.6060/mhc160959s WOS Scopus РИНЦ

Full text from publisher

Web of science	WOS:000405134200017
Scopus	2-s2.0-85052806490
Elibrary	29332741
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