Synthesis of Ionic Biologically Active Conjugates from Trolox and alpha-Tocopherol Succinates

Synthesis of Ionic Biologically Active Conjugates from Trolox and alpha-Tocopherol Succinates Full article

Journal

Chemistry of Natural Compounds
ISSN: 0009-3130 , E-ISSN: 1573-8388

Output data

Year: 2016, Volume: 52, Number: 6, Pages: 1015-1019 Pages count : 5 DOI: 10.1007/s10600-016-1850-x

Tags

trolox; alpha-tocopherol; succinates; diethanolamine; nitroxyl radical amino-TEMPO; ammonium salts; ionic conjugates; water solubility

Authors

Yushkova Yu.V. ¹ , Morozov S.V. ^1,2 , Chernyak E.I. ¹ , Grigor'ev I.A. ^1,3

Affiliations

1	(Данные Web of science) Russian Acad Sci, Siberian Branch, NN Vorozhtsov Novosibirsk Inst Organ Chem, 9Prosp Akad Lavrenteva, Novosibirsk 630090, Russia
2	(Данные Web of science) Novosibirsk State Univ, 2 Pirogova St, Novosibirsk 630090, Russia
3	(Данные Web of science) EN Meshalkin Novosibirsk Sci Res Inst Circulat Pa, 15 Rechkunovskaya St, Novosibirsk 630055, Russia

Six ionic conjugates with nitroxyl radical amino-TEMPO and diethanolamine as the amines were synthesized from trolox and alpha-tocopherol succinates. The water solubility of the synthesized ammonium salts was determined. It was shown that formation of the trolox succinate salts increased the water solubility whereas this phenomenon was not observed for alpha-tocopherol succinates.

Yushkova Y.V. , Morozov S.V. , Chernyak E.I. , Grigor'ev I.A.
Synthesis of Ionic Biologically Active Conjugates from Trolox and alpha-Tocopherol Succinates
Chemistry of Natural Compounds. 2016. V.52. N6. P.1015-1019. DOI: 10.1007/s10600-016-1850-x WOS Scopus РИНЦ

Published online:	Oct 25, 2016
Published print:	Nov 1, 2016

Web of science	WOS:000387344100012
Scopus	2-s2.0-85043776277
Elibrary	41786077
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