Characterization and cytotoxicity studies of thiol-modified polystyrene microbeads doped with [{Mo6X8}(NO3)(6)](2-) (X=Cl, Br, I)

Characterization and cytotoxicity studies of thiol-modified polystyrene microbeads doped with [{Mo6X8}(NO3)(6)](2-) (X=Cl, Br, I) Full article

Journal

Polymers for Advanced Technologies
ISSN: 1042-7147 , E-ISSN: 1099-1581

Output data

Year: 2016, Volume: 27, Number: 7, Pages: 922-928 Pages count : DOI: 10.1002/pat.3749

Tags

molybdenum cluster complex; photoluminescence; polystyrene microbeads; cytotoxicity

Authors

Vorotnikova Natalya A. ^1,2 , Efremova Olga A. ^3,4 , Tsygankova Alphiya R. ^1,5 , Brylev Konstantin A. ^1,5 , Edeleva Mariya V. ^2,6 , Kurskaya Olga. G. ⁷ , Sutherland Andrew J. ³ , Shestopalov Alexandr M. ⁷ , Mironov Yuri V. ^1,5 , Shestopalov Michael A. ^1,2

Affiliations

1	(Данные Web of science) Nikolaev Inst Inorgan Chem SB RAS, 3 Acad Lavrentiev Ave, Novosibirsk 630090, Russia
2	(Данные Web of science) Sci Inst Clin & Expt Lymphol, 2 Timakova Str, Novosibirsk 630090, Russia
3	(Данные Web of science) Aston Univ, Dept Chem Engn & Appl Chem, Birmingham B4 7ET, W Midlands, England
4	(Данные Web of science) Univ Hull, Dept Chem, Kingston Upon Hull HU6 7RX, N Humberside, England
5	(Данные Web of science) Novosibirsk State Univ, 2 Pirogova Str, Novosibirsk 630090, Russia
6	(Данные Web of science) Novosibirsk Inst Organ Chem SB RAS, 9 Acad Lavrentiev Ave, Novosibirsk 630090, Russia
7	(Данные Web of science) Res Inst Expt & Clin Med, Novosibirsk 630090, Russia

Halide octahedral molybdenum clusters [{Mo6X8}L-6](n-) possess luminescence properties that are highly promising for biological applications. These properties are rather dependent on the nature of both the inner ligands X (i.e. Cl, Br, or I) and the apical organic or inorganic ligands L. Herein, the luminescence properties and the toxicity of thiol-modified polystyrene microbeads (PS-SH) doped with [{Mo6X8}(NO3)(6)](2-) (X=Cl, Br, I) were studied and evaluated using human epidermoid larynx carcinoma (Hep2) cell cultures. According to our data, the photoluminescence quantum yield of {Mo6I8}@PS-SH is significantly higher (0.04) than that of {Mo6Cl8}@PS-SH (<0.005) and {Mo6Br8}@PS-SH (<0.005). Treatment of Hep2 cells with {Mo6X8}@PS-SH showed that all three types of doped microbeads had no significant effect on the viability and proliferation of the cells. Copyright (c) 2016 John Wiley & Sons, Ltd.

Vorotnikova N.A. , Efremova O.A. , Tsygankova A.R. , Brylev K.A. , Edeleva M.V. , Kurskaya O.G. , Sutherland A.J. , Shestopalov A.M. , Mironov Y.V. , Shestopalov M.A.
Characterization and cytotoxicity studies of thiol-modified polystyrene microbeads doped with [{Mo6X8}(NO3)(6)](2-) (X=Cl, Br, I)

Polymers for Advanced Technologies. 2016. V.27. N7. P.922-928. DOI: 10.1002/pat.3749 WOS Scopus РИНЦ

Full text from publisher

Published online:	Jan 11, 2016
Published print:	Jul 1, 2016

Web of science	WOS:000378733400009
Scopus	2-s2.0-84954556852
Elibrary	27054246
OpenAlex	W2225511831