ANALGESIC EFFECT OF SEVERAL NONSTEROIDAL ANTI-INFLAMMATORY DRUG NANOAEROSOLS

ANALGESIC EFFECT OF SEVERAL NONSTEROIDAL ANTI-INFLAMMATORY DRUG NANOAEROSOLS Full article

Journal

Pharmaceutical Chemistry Journal
ISSN: 0091-150X , E-ISSN: 1573-9031

Output data

Year: 2016, Volume: 49, Number: 10, Pages: 680-682 Pages count : DOI: 10.1007/s11094-016-1352-y

Tags

nonsteroidal anti-inflammatory drugs; nanoaerosols; indomethacin; butadion; diclofenac

Authors

An'kov S. V. ¹ , Tolstikova T. G. ¹ , Onishchuk A. A. ^2,5 , Khvostov M. V. ¹ , Sorokina I. V. ¹ , Baklanov A. M. ² , Fomin V. M. ³ , Boldyrev V. V. ^4,5

Affiliations

1	(Данные Web of science) Russian Acad Sci, NN Vorozhtsov Novosibirsk Inst Organ Chem, Siberian Branch, Prosp Akad Lavrenteva 9, Novosibirsk 630090, Russia
2	(Данные Web of science) Russian Acad Sci, VV Voevodsky Inst Chem Kinet & Combust, Siberian Branch, Ul Inst Skaya 3, Novosibirsk 630090, Russia
3	(Данные Web of science) Russian Acad Sci, SA Khristianovich Inst Theoret & Appl Mech, Siberian Branch, Ul Inst Skaya 4-1, Novosibirsk 630090, Russia
4	(Данные Web of science) Russian Acad Sci, Inst Solid State Chem & Mechnochem, Siberian Branch, Ul Kutateladze 18, Novosibirsk 630090, Russia
5	(Данные Web of science) Novosibirsk State Natl Res Univ, Ul Pirogova 2, Novosibirsk 630090, Russia

The analgesic activities of nanoaerosols of the nonsteroidal anti-inflammatory drugs indomethacin, butadion, and diclofenac were studied. It was found that nanoaerosol delivery of these drugs gave analgesic activities that were comparable to those of oral delivery 5 - 8 min after administration at doses that were 3 - 5 orders of magnitude lower.

An'kov S.V. , Tolstikova T.G. , Onishchuk A.A. , Khvostov M.V. , Sorokina I.V. , Baklanov A.M. , Fomin V.M. , Boldyrev V.V.
ANALGESIC EFFECT OF SEVERAL NONSTEROIDAL ANTI-INFLAMMATORY DRUG NANOAEROSOLS
Pharmaceutical Chemistry Journal. 2016. V.49. N10. P.680-682. DOI: 10.1007/s11094-016-1352-y WOS Scopus РИНЦ

Аньков С.В. , Толстикова Т.Г. , Онищук А.А. , Хвостов М.В. , Сорокина И.В. , Бакланов А.М. , Фомин В.М. , Болдырев В.В.
Анальгетический эффект наноаэрозольной формы некоторых нестероидных противовоспалительных препаратов
Химико-фармацевтический журнал (PHARM CHEM J+). 2015. Т.49. №10. С.37-39. РИНЦ

Published print:	Jan 1, 2016
Published online:	Feb 3, 2016

Web of science	WOS:000406145000008
Scopus	2-s2.0-84957589990
Elibrary	26954952
OpenAlex	W2300721582