Selective mono- and diamination of some polyhalogenbenzenes in anhydrous ammonia

Selective mono- and diamination of some polyhalogenbenzenes in anhydrous ammonia Full article

Journal

Journal of Fluorine Chemistry
ISSN: 0022-1139

Output data

Year: 2015, Volume: 180, Pages: 98-102 Pages count : DOI: 10.1016/j.jfluchem.2015.09.003

Tags

Polychlorofluorobenzenes; Anhydrous ammonia; Aminodefluorination; Nucleophilic substitution; Polyhalogenaromatic amines

Authors

Rodionov Vladimir I. ¹ , Vaganova Tamara A. ¹ , Malykhin Evgenij V. ¹

Affiliations

1	(Данные Web of science) Russian Acad Sci, NN Vorozhtsov Novosibirsk Inst Organ Chem, Siberian Branch, Novosibirsk 630090, Russia

Aminodefluorination of polyhalogenbenzenes (chloropentafluoro-, 1,3-dichlorotetrafluoro-, sym-trichlorotrifluoro-, 1,2,3,5-tetrafluoro- and 1,2,4,5-tetrafluoro-3-trifluoromethylbezenes) in anhydrous ammonia was investigated. The optimal conditions for selective preparation of mono- and diamino derivatives, which are ensured by the reaction temperature, were elucidated. In some examples of diamine synthesis, in order to improve the selectivity of second aminodefluorination, it is advisable to separate the isomeric monoamino derivatives produced in the first step of the synthesis. (C) 2015 Elsevier B.V. All rights reserved.

Rodionov V.I. , Vaganova T.A. , Malykhin E.V.
Selective mono- and diamination of some polyhalogenbenzenes in anhydrous ammonia
Journal of Fluorine Chemistry. 2015. V.180. P.98-102. DOI: 10.1016/j.jfluchem.2015.09.003 WOS Scopus РИНЦ

Published print:

Dec 1, 2015

Web of science	WOS:000366768800009
Scopus	2-s2.0-84941662557
Elibrary	24949411
OpenAlex	W1450874360