Abstract: Currently, the chemistry of organofluorine compounds is a leading and rapidly developing area of organic chemistry. Fluorine present in a molecule largely determines its specific chemical and biological properties. This thematic issue covers the trends of organofluorine chemistry that have been actively developed in Russia the last 15 - 20 years. The review describes nucleophilic substitution and heterocyclization reactions involving fluorinated arenes and quinones and skeletal cationoid rearrangements in the polyfluoroarene series. The transformations involving CF3-substituted carbocations and radical cations are considered. Heterocyclization and oxidative addition reactions of trifluoroacetamide derivatives and transformations of the organic moiety in polyfluorinated organoboranes and borates with retention of the carbon - boron bond are discussed. Particular attention is devoted to catalytic olefination using freons as an efficient synthetic route to fluorinated compounds. The application of unsymmetrical fluorine-containing N-heterocyclic carbene ligands as catalysts for olefin metathesis is demonstrated. A variety of classes of organofluorine compounds are considered, in particular, polyfluorinated arenes and 1,2-diaminobenzenes, 1-halo-2-trifluoroacetylacetylenes, alpha-fluoronitro compounds, fluorinated heterocycles, 2-hydrazinylidene-1,3-dicarbonyl derivatives, imines and silanes. The potential practical applications of organofluorine compounds in fundamental organic chemistry, materials science and biomedicine are outlined.

Cite: Politanskaya L.V. , Selivanova G.A. , Panteleeva E.V. , Tretyakov E.V. , Platonov V.E. , Nikul'shin P.V. , Vinogradov A.S. , Zonov Y.V. , Karpov V.M. , Mezhenkova T.V. , Vasilyev A.V. , Koldobskii A.B. , Shilova O.S. , Morozova S.M. , Burgart Y.V. , Shchegolkov E.V. , Saloutin V.I. , Sokolov V.B. , Aksinenko A.Y. , Nenajdenko V.G. , Moskalik M.Y. , Astakhova V.V. , Shainyan B.A. , Tabolin A.A. , Ioffe S.L. , Muzalevskiy V.M. , Balenkova E.S. , Shastin A.V. , Tyutyunov A.A. , Boiko V.E. , Igumnov S.M. , Dilman A.D. , Adonin N.Y. , Bardin V.V. , Masoud S.M. , Vorobyeva D.V. , Osipov S.N. , Nosova E.V. , Lipunova G.N. , Charushin V.N. , Prima D.O. , Makarov A.G. , Zibarev A.V. , Trofimov B.A. , Sobenina L.N. , Belyaeva K.V. , Sosnovskikh V.Y. , Obydennov D.L. , Usachev S.A.
Organofluorine chemistry: promising growth areas and challenges
Russian Chemical Reviews. 2019. V.88. N5. P.425-569. DOI: 10.1070/RCR4871 WOS Scopus РИНЦ

ArticleLinkType.TRANSLATED_TO_ORIGINAL: Политанская Л.В. , Селиванова Г.А. , Пантелеева Е.В. , Третьяков Е.В. , Платонов В.Е. , Никульшин П.В. , Виноградов А.С. , Зонов Я.В. , Карпов В.М. , Меженкова Т.В. , Васильев А.В. , Колдобский А.Б. , Шилова О.С. , Морозова С.М. , Бургарт Я.В. , Щегольков Е.В. , Салоутин В.И. , Соколов В.Б. , Аксиненко А.Ю. , Ненайденко В.Г. , Москалик М.Ю. , Астахова В.В. , Шаинян Б.А. , Таболин А.А. , Иоффе С.Л. , Музалевский В.М. , Баленкова Е.С. , Шастин А.В. , Тютюнов А.А. , Бойко В.Э. , Игумнов С.М. , Дилман А.Д. , Адонин Н.Ю. , Бардин В.В. , Масоуд С.М. , Воробьева Д.В. , Осипов С.Н. , Носова Э.В. , Липунова Г.Н. , Чарушин В.Н. , Прима Д.О. , Макаров А.Г. , Зибарев А.В. , Трофимов Б.А. , Собенина Л.Н. , Беляева К.В. , Сосновских В.Я. , Обыденнов Д.Л. , Усачев С.А.
Перспективные точки роста и вызовы фторорганической химии
Успехи химии/Uspekhi Khimii. 2019. Т.88. №5. С.425-569. DOI: 10.1070/RCR4871?locatt=label:RUSSIAN РИНЦ

Dates:

Published online:	Apr 30, 2019
Published print:	May 1, 2019

Identifiers:

Web of science	WOS:000466355000002
Scopus	2-s2.0-85066251313
Elibrary	41801075
OpenAlex	W2799524300

Altmetrics: