Synthesis and analgesic activity of octahydro-2H-chromenols, derivatives of aliphatic ketones Full article
| Journal |
Russian Chemical Bulletin
ISSN: 1066-5285 , E-ISSN: 1573-9171 |
||||
|---|---|---|---|---|---|
| Output data | Year: 2019, Volume: 68, Number: 5, Pages: 1061-1066 Pages count : 6 DOI: 10.1007/s11172-019-2520-5 | ||||
| Tags | monoterpenoids; montmorillonite K10; heterocyclic compounds; analgesic activity | ||||
| Authors |
|
||||
| Affiliations |
|
Abstract:
A series of compounds with a hydrogenated 2H-chromene skeleton was synthesized by the reaction of ketones and available para-menthane monoterpenoid ()-isopulegol. A condensation product of ()-isopulegol with the monoterpene ketone l-menthone was synthesized for the first time. The synthesized heterocycles were tested for analgesic activity and compounds with high analgesic activity in the in vivo tests were identified.
Cite:
Il'ina I.V.
, Korchagina D.V.
, Morozova E.A.
, Tolstikova T.G.
, Volcho K.P.
, Salakhutdinov N.F.
Synthesis and analgesic activity of octahydro-2H-chromenols, derivatives of aliphatic ketones
Russian Chemical Bulletin. 2019. V.68. N5. P.1061-1066. DOI: 10.1007/s11172-019-2520-5 WOS Scopus РИНЦ OpenAlex
Synthesis and analgesic activity of octahydro-2H-chromenols, derivatives of aliphatic ketones
Russian Chemical Bulletin. 2019. V.68. N5. P.1061-1066. DOI: 10.1007/s11172-019-2520-5 WOS Scopus РИНЦ OpenAlex
Original:
Ильина И.В.
, Корчагина Д.В.
, Морозова Е.А.
, Толстикова Т.Г.
, Волчо К.П.
, Салахутдинов Н.Ф.
Синтез и анальгетическая активность октагидро-2H-хроменолов - производных алифатических кетонов
Известия Академии наук. Серия химическая.(RUSS CHEM B+). 2019. №5. С.1061-1066. РИНЦ
Синтез и анальгетическая активность октагидро-2H-хроменолов - производных алифатических кетонов
Известия Академии наук. Серия химическая.(RUSS CHEM B+). 2019. №5. С.1061-1066. РИНЦ
Dates:
| Published print: | May 1, 2019 |
| Published online: | Jun 11, 2019 |
Identifiers:
| Web of science: | WOS:000471201700018 |
| Scopus: | 2-s2.0-85067041253 |
| Elibrary: | 41622327 |
| OpenAlex: | W2951394690 |