Complex Investigation of the Effects of Lambertianic Acid Amide in Female Mice under Conditions of Social Discomfort Full article
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Bulletin of Experimental Biology and Medicine
ISSN: 0007-4888 |
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| Output data | Year: 2014, Volume: 157, Number: 5, Pages: 583-587 Pages count : 5 DOI: 10.1007/s10517-014-2621-y | ||||||
| Tags | female mice; social discomfort; lambertianic acid derivatives | ||||||
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Abstract:
The effects of chronic administration of a new substance lambertianic acid amide and previously synthesized methyl ester of this acid were compared in female mice living under conditions of social discomfort. For modeling social discomfort, female mouse was housed for 30 days in a cage with aggressive male mouse kept behind a transparent perforated partition and observed its confrontations with another male mouse daily placed to the cage. The new agent more effectively than lambertianic acid methyl ester improved communicativeness and motor activity of animals, reduced hypertrophy of the adrenal glands, and enhanced catalase activity in the blood. These changes suggest that lambertianic acid amide produces a pronounced stress-protective effect under conditions of social discomfort.
Cite:
Avgustinovich D.F.
, Fomina M.K.
, Sorokina I.V.
, Tolstikova T.G.
Complex Investigation of the Effects of Lambertianic Acid Amide in Female Mice under Conditions of Social Discomfort
Bulletin of Experimental Biology and Medicine. 2014. V.157. N5. P.583-587. DOI: 10.1007/s10517-014-2621-y WOS Scopus РИНЦ OpenAlex
Complex Investigation of the Effects of Lambertianic Acid Amide in Female Mice under Conditions of Social Discomfort
Bulletin of Experimental Biology and Medicine. 2014. V.157. N5. P.583-587. DOI: 10.1007/s10517-014-2621-y WOS Scopus РИНЦ OpenAlex
Original:
Августинович Д.Ф.
, Маренина М.К.
, Сорокина И.В.
, Толстикова Т.Г.
Комплексное исследование эффектов амида ламбертиановой кислоты у самок мышей, находящихся в условиях социального дискомфорта
Бюллетень экспериментальной биологии и медицины (B EXP BIOL MED+). 2014. Т.157. №5. С.599-603. РИНЦ
Комплексное исследование эффектов амида ламбертиановой кислоты у самок мышей, находящихся в условиях социального дискомфорта
Бюллетень экспериментальной биологии и медицины (B EXP BIOL MED+). 2014. Т.157. №5. С.599-603. РИНЦ
Dates:
| Published print: | Sep 1, 2014 |
| Published online: | Sep 26, 2014 |
Identifiers:
| Web of science: | WOS:000343135900013 |
| Scopus: | 2-s2.0-84921937405 |
| Elibrary: | 22775346 |
| OpenAlex: | W1977995228 |