A novel method for the sterically shielded pyrrolidine nitroxides synthesis using donor–acceptor cyclopropanes Full article
| Journal |
Tetrahedron Letters
ISSN: 0040-4039 |
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| Output data | Year: 2023, Volume: 123, Pages: 154546 Pages count : 1 DOI: 10.1016/j.tetlet.2023.154546 | ||||
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| Affiliations |
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Funding (1)
| 1 | Российский Научный Фонд | 21-73-00281 |
Abstract:
Sterically shielded nitroxides were shown to demonstrate resistance to bioreduction. For this reason, they are attracting much interest as spin labels and probes for in-cell and in vivo EPR and NMR applications. Formal [3 + 2] cycloaddition reaction of donor–acceptor cyclopropanes with propionitrile provided 1-pyrrolines which were converted to the new sterically shielded achiral pyrrolidine nitroxides via several steps.
Cite:
Taratayko A.I.
, Trakhinina S.Y.
, Lomanovich K.A.
, Kirilyuk I.A.
A novel method for the sterically shielded pyrrolidine nitroxides synthesis using donor–acceptor cyclopropanes
Tetrahedron Letters. 2023. V.123. P.154546. DOI: 10.1016/j.tetlet.2023.154546 WOS РИНЦ OpenAlex
A novel method for the sterically shielded pyrrolidine nitroxides synthesis using donor–acceptor cyclopropanes
Tetrahedron Letters. 2023. V.123. P.154546. DOI: 10.1016/j.tetlet.2023.154546 WOS РИНЦ OpenAlex
Dates:
| Submitted: | Apr 10, 2023 |
| Accepted: | May 8, 2023 |
| Published online: | May 12, 2023 |
Identifiers:
| Web of science: | WOS:001012380900001 |
| Elibrary: | 61808483 |
| OpenAlex: | W4376126308 |