Abstract: Nitroxide biradicals are efficient polarizing agents in dynamic nuclear polarization (DNP) solid-state nuclear magnetic resonance. Many recently reported radicals possess substantial DNP efficiency in organic solvents but have poor solubility in water media which is unfavorable for biological applications. In this paper, we report DNP efficiency at a high magnetic field for two water-soluble biradicals resistant to reducing media. Water solubility was achieved by obtaining the radicals in the form of quaternary ammonium salts. Parameters of hyperfine interaction and exchange interaction were quantified by EPR spectroscopy, and their influence on the DNP effect was determined. The resistance of the biradicals to strongly reducing media was characterized. High stability was achieved using tetraethyl substituents and pyrrolidine moieties.

Cite: Asanbaeva N.B. , Dobrynin S.A. , Morozov D.A. , Haro-Mares N. , Gutmann T. , Buntkowsky G. , Bagryanskaya E.G.
An EPR Study on Highly Stable Nitroxyl-Nitroxyl Biradicals for Dynamic Nuclear Polarization Applications at High Magnetic Fields
Molecules. 2023. V.28. N4. P.1926. DOI: 10.3390/molecules28041926 WOS Scopus РИНЦ OpenAlex

Dates:

Submitted:	Feb 2, 2023
Accepted:	Feb 15, 2023
Published print:	Feb 17, 2023

Identifiers:

Web of science:	WOS:000939993200001
Scopus:	2-s2.0-85149053613
Elibrary:	60719654
OpenAlex:	W4321375651

Citing:

DB	Citing
OpenAlex	6
Web of science	3
Scopus	3

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