ANTIBACTERIAL ACTIVITY OF POLYPHENOLS DERIVED MECHANOCHEMICALLY FROM NATURAL RAW MATERIALS
Full article
| Journal |
Журнал Сибирского федерального университета. Серия: Химия (Journal of Siberian Federal University. Chemistry)
|
| Output data |
Year: 2023,
Volume: 16,
Number: 1,
Pages: 16-27
Pages count
: 12
|
| Tags |
MECHANOCHEMICAL ACTIVATION, POLYPHENOLS, MELANIN, HUMIC SUBSTANCES, BIOLOGICAL ACTIVITY |
| Authors |
Lomovskiy Igor O.
1
,
Koptev Viacheslav Yu.
2
,
Balybina Natalia Yu.
2
,
Tikhova Vera D.
3
,
Skripkina Tatiana S.
1
,
Lomovsky Oleg I.
1
|
| Affiliations |
| 1 |
Institute of Solid State Chemistry and Mechanochemistry SB RAS Novosibirsk, Russian Federation
|
| 2 |
Institute of Experimental Veterinary of Siberia and Far East Siberian Federal Scientifc Centre of Agrobiotechnologies RAS Krasnoobsk, Novosibirsk region, Russian Federation
|
| 3 |
N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, Novosibirsk, Russian Federation
|
|
This study focuses on bactericidal activity of a number of biomass-derived polyphenols (humic substances and melanins) obtained by mechanochemical activation of the brown coal and husk of buckwheat mixed with a solid oxidizing or reducing agents against opportunistic pathogens relevant to the poultry industry: Salmonella typhimurium, Shigella sonnei, Escherichia coli, Pasteurella multocida, Yersinia pseudotuberculosis, Streptococcus pyogenes, Staphylococcus aureus, and Staphylococcus epidermidis. The studied polyphenols are active against bacteria belonging to the family Enterobacteriaceae (Salmonella typhimurium, Shigella sonnei, Escherichia coli, and Yersinia pseudotuberculosis) after being subjected to mechanochemical activation in the presence of sodium percarbonate. Almost all the studied samples, except for those exposed to treatment with zinc, were active against bacteria Pasteurella multocida (the family Pasteurellacеae) and Staphylococcus epidermidis (the family Staphylococcаcеae). The samples active against bacteria Streptococcus pyogenes (the family Streptococcacеae) and Staphylococcus aureus (the family Staphylococcacеae) can be obtained by mechanochemical interaction with sodium percarbonate under certain conditions.