Preparation of 2-unsubstituted 5-aryl(hetaryl)-1-hydroxy-1H-imidazoles from of 4-aryl(hetaryl)-1-hydroxy-2,5-dihydro-1H-imidazole-2-carboxylic acid 3-oxides

Preparation of 2-unsubstituted 5-aryl(hetaryl)-1-hydroxy-1H-imidazoles from of 4-aryl(hetaryl)-1-hydroxy-2,5-dihydro-1H-imidazole-2-carboxylic acid 3-oxides Full article

Journal

Chemistry of Heterocyclic Compounds
ISSN: 0009-3122 , E-ISSN: 1573-8353

Output data

Year: 2023, Volume: 59, Number: 11-12, Pages: 752-757 Pages count : 6 DOI: 10.1007/s10593-024-03268-5

Tags

glyoxylic acid hydroxyaminooximes 1-hydroxy-2,5-dihydro-1H-imidazole 3-oxides 1-hydroxy-1H-imidazoles

Authors

Nikolaenkova Elena B. ¹ , Grishchenko Stanislav Yu. ¹ , Rybalova Tatyana V. ¹ , Tikhonov Alexei Ya. ¹

Affiliations

1	N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences

Alkylaromatic 1-hydroxyamino-2-oximes reacted at the hydroxyamino group with glyoxylic acid hydrate, providing 4-aryl(hetaryl)-1-hydroxy-2,5-dihydro-1H-imidazole-2-carboxylic acid 3-oxides that were converted upon heating into 5-aryl(hetaryl)-1-hydroxy-1H-imidazoles containing a hydrogen atom at the heterocycle position 2.

Nikolaenkova E.B. , Grishchenko S.Y. , Rybalova T.V. , Tikhonov A.Y.
Preparation of 2-unsubstituted 5-aryl(hetaryl)-1-hydroxy-1H-imidazoles from of 4-aryl(hetaryl)-1-hydroxy-2,5-dihydro-1H-imidazole-2-carboxylic acid 3-oxides
Chemistry of Heterocyclic Compounds. 2023. V.59. N11-12. P.752-757. DOI: 10.1007/s10593-024-03268-5 WOS РИНЦ OpenAlex

Submitted:	Apr 18, 2023
Accepted:	Sep 19, 2023

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