First spin-labeled cytisine derivatives

First spin-labeled cytisine derivatives Full article

Journal

Chemistry of Natural Compounds
ISSN: 0009-3130 , E-ISSN: 1573-8388

Output data

Year: 2013, Volume: 49, Number: 2, Pages: 311-315 Pages count : DOI: 10.1007/s10600-013-0588-y

Tags

cytisine; nitroxyl radicals; spin labels; LD50

Authors

Polienko Yu. F. ¹ , Vinogradova V. I. ² , Sagdullaev Sh. Sh. ² , Abdullaev N. D. ² , Gatilov Yu. V. ¹ , Grigor'ev I. A. ¹

Affiliations

1	(Данные Web of science) Russian Acad Sci, Siberian Branch, NN Vorozhtsov Novosibirsk Inst Organ Chem, Novosibirsk 630090, Russia
2	(Данные Web of science) Acad Sci Uzbek, S Yu Yunusov Inst Chem Plant Subst, Tashkent 100170, Uzbekistan

Spin-labeled cytisine derivatives containing stable pyrrolidine and piperidine nitroxyl radicals were synthesized by acylation and alkylation of the secondary amine. Toxicological studies showed that introduction of the nitroxyl group decreased significantly the general toxicity.

Polienko Y.F. , Vinogradova V.I. , Sagdullaev S.S. , Abdullaev N.D. , Gatilov Y.V. , Grigor'ev I.A.
First spin-labeled cytisine derivatives
Chemistry of Natural Compounds. 2013. V.49. N2. P.311-315. DOI: 10.1007/s10600-013-0588-y WOS Scopus РИНЦ OpenAlex

Published print:	May 1, 2013
Published online:	Jun 13, 2013

≡ Web of science:	WOS:000320770600027
≡ Scopus:	2-s2.0-84879800356
≡ Elibrary:	20439096
≡ OpenAlex:	W1978863536