Sulfonium derivatives of thioxanthenone, a new class of photodetritylating agents for microarray oligonucleotide synthesis Full article
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Russian Journal of Bioorganic Chemistry
ISSN: 1068-1620 |
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| Output data | Year: 2010, Volume: 36, Number: 1, Pages: 130-132 Pages count : DOI: 10.1134/S1068162010010152 | ||||
| Tags | photogenerators of acids; oligodeoxyribonucleotides; thioxanthenone; trityl cation | ||||
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Abstract:
The usability of a new class of photo acids, namely, sulfonium hexaphosphates based on thioxanthenone, for the removal of the dimethoxytrityl protective group in the process of oligonucleotide synthesis has been studied in order to search for new detritylating agents for microarray oligodeoxyribonucleotide synthesis. 2,4-Diethyl-9-oxo-10-(4-heptyloxyphenyl)-9H-thioxanthenium hexafluorophosphate has been successfully used for the solid-phase synthesis of (dT)(10).
Cite:
Sinyakov A.N.
, Ryabinin A.A.
, Maksakova G.A.
, Shelkovnikov V.V.
, Loskutov V.A.
, Vasil'ev E.V.
, Shekleina N.V.
Sulfonium derivatives of thioxanthenone, a new class of photodetritylating agents for microarray oligonucleotide synthesis
Russian Journal of Bioorganic Chemistry. 2010. V.36. N1. P.130-132. DOI: 10.1134/S1068162010010152 WOS Scopus РИНЦ OpenAlex
Sulfonium derivatives of thioxanthenone, a new class of photodetritylating agents for microarray oligonucleotide synthesis
Russian Journal of Bioorganic Chemistry. 2010. V.36. N1. P.130-132. DOI: 10.1134/S1068162010010152 WOS Scopus РИНЦ OpenAlex
Original:
Синяков А.Н.
, Рябинин А.А.
, Максакова Г.А.
, Шелковников В.В.
, Лоскутов В.А.
, Васильев Е.В.
, Васильева Н.В.
Сульфониевые производные тиоксантенона новый класс соединений для фотодетритилирования в микрочиповом олигонуклеотидном синтезе
Биоорганическая химия (RUSS J BIOORG CHEM+). 2010. Т.31. №1. С.139-141. РИНЦ
Сульфониевые производные тиоксантенона новый класс соединений для фотодетритилирования в микрочиповом олигонуклеотидном синтезе
Биоорганическая химия (RUSS J BIOORG CHEM+). 2010. Т.31. №1. С.139-141. РИНЦ
Dates:
| Published print: | Jan 1, 2010 |
| Published online: | Feb 2, 2010 |
Identifiers:
| Web of science: | WOS:000274211500015 |
| Scopus: | 2-s2.0-77649092151 |
| Elibrary: | 15313256 |
| OpenAlex: | W2141938212 |