Antioxidative properties of nitroxyl radicals and hydroxyamines in reactions with triplet and deaminated kynurenine Full article
| Journal |
Russian Chemical Bulletin
ISSN: 1066-5285 , E-ISSN: 1573-9171 |
||||||
|---|---|---|---|---|---|---|---|
| Output data | Year: 2010, Volume: 59, Number: 1, Pages: 66-74 Pages count : DOI: 10.1007/s11172-010-0046-y | ||||||
| Tags | kynurenine; 4-(2-aminophenyl)-4-oxocrotonic acid; triplet excited state; quenching reactions; laser flash photolysis; nitroxyl radicals; hydroxylamines | ||||||
| Authors |
|
||||||
| Affiliations |
|
Abstract:
The reactions of triplet kynurenine and 4-(2-aminophenyl)-4-oxocrotonic acid, formed upon the thermal decomposition of kynurenine, with nitroxyl radicals and cyclic N-hydroxylamines were studied. Nitroxyl radicals were found to quench efficiently the triplet state of kynurenine (rate constant 3-6 center dot.10(8) L mol(-1) s(-1)). The quenching proceeds via the spin-exchange mechanism and affords no new products. Neither nitroxyl radicals, nor hydroxyl-lamines react with 4-(2-aminophenyl)-4-oxocrotonic acid under conditions similar to physiological.
Cite:
Yan'shole V.V.
, Kirilyuk I.A.
, Grigor'ev I.A.
, Morozov S.V.
, Tsentalovicha Y.P.
Antioxidative properties of nitroxyl radicals and hydroxyamines in reactions with triplet and deaminated kynurenine
Russian Chemical Bulletin. 2010. V.59. N1. P.66-74. DOI: 10.1007/s11172-010-0046-y WOS Scopus РИНЦ OpenAlex
Antioxidative properties of nitroxyl radicals and hydroxyamines in reactions with triplet and deaminated kynurenine
Russian Chemical Bulletin. 2010. V.59. N1. P.66-74. DOI: 10.1007/s11172-010-0046-y WOS Scopus РИНЦ OpenAlex
Original:
Яньшоле В.В.
, Кирилюк И.А.
, Григорьев И.А.
, Морозов С.В.
, Центалович Ю.П.
Изучение антиоксидантных свойств нитроксильных радикалов и гидроксиламинов при взаимодействии с триплетным и дезаминированным кинуренином
Известия Академии наук. Серия химическая.(RUSS CHEM B+). 2010. №1. С.67. РИНЦ
Изучение антиоксидантных свойств нитроксильных радикалов и гидроксиламинов при взаимодействии с триплетным и дезаминированным кинуренином
Известия Академии наук. Серия химическая.(RUSS CHEM B+). 2010. №1. С.67. РИНЦ
Dates:
| Published print: | Jan 1, 2010 |
| Published online: | Apr 19, 2010 |
Identifiers:
| Web of science: | WOS:000277959600006 |
| Scopus: | 2-s2.0-77955856339 |
| Elibrary: | 15329241 |
| OpenAlex: | W2048882159 |