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The Complexes of Drugs with Carbohydrate-Containing Plant Metabolites as Pharmacologically Promising Agents Full article

Journal Mini-Reviews in Medicinal Chemistry
ISSN: 1389-5575 , E-ISSN: 1875-5607
Output data Year: 2009, Volume: 9, Number: 11, Pages: 1317-1328 Pages count : DOI: 10.2174/138955709789878123
Tags Complexation; plant metabolites; glycyrrhizic acid; arabinogalactan; stevioside
Authors Tolstikova T. G. 1 , Khvostov M. V. 1 , Bryzgalov A. O. 1
Affiliations
1 (Данные Web of science) Novosibirsk Organ Chem Inst, Novosibirsk 630090, Russia

Abstract: Complexation of known drugs with carbohydrate-containing plant metabolites is a promising way to synthesize new drugs that does not only save pharmacological properties of initial agent but also acquire a number of advantageous features such as increased water solubility, bioavailability and decreased toxicity. This review reports on the development and pharmacological evaluation of novel complexes of various well-known drugs with vegetable coplexation agents: glycyrrhizic acid, Stevia glycosides, gypsogenin tetraoside, pectin, xyloglucan, arabinogalactan. The aim of this review is to describe advantages of the new approach, suggested by authors, in the development of low toxic and high-performance drugs.
Cite: Tolstikova T.G. , Khvostov M.V. , Bryzgalov A.O.
The Complexes of Drugs with Carbohydrate-Containing Plant Metabolites as Pharmacologically Promising Agents
Mini-Reviews in Medicinal Chemistry. 2009. V.9. N11. P.1317-1328. DOI: 10.2174/138955709789878123 WOS Scopus РИНЦ OpenAlex
Dates:
Published print: Oct 1, 2009
Identifiers:
Web of science: WOS:000272794800007
Scopus: 2-s2.0-73349085554
Elibrary: 15309336
OpenAlex: W2140733649
Citing:
DB Citing
Web of science 55
Scopus 69
Elibrary 98
OpenAlex 66
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