Improved synthesis of 1-hydroxy-2,2,5,5-tetramethyl-3-imidazoline 3-oxide (HTIO) Full article
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Synthetic Communications
ISSN: 0039-7911 , E-ISSN: 1532-2432 |
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| Output data | Year: 2006, Volume: 36, Number: 19, Pages: 2763-2768 Pages count : 6 DOI: 10.1080/00397910600767272 | ||||
| Tags | aldonitrone; 2,2-dialkoxypropane; HTIO; 3-imidazoline 3-oxide; nitroxide | ||||
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Abstract:
A simple, efficient, mild, and reproducible method for the synthesis of 1-hydroxy-2,2,5,5-tetramethyl-3-imidazoline3-oxide is described. The method is based on the condensation of 2-hydroxyamino-2-methylpropanal oxime with 2,2-diethoxypropane in the presence of an equimolar quantity of acetic acid. Cost-effectiveness of the condensation procedure could be also achieved by replacing 2,2-diethoxypropane with less expensive 2,2-dimethoxypropane.
Cite:
Polienko J.F.
, Schanding T.
, Voinov M.A.
, Grigor'ev I.A.
Improved synthesis of 1-hydroxy-2,2,5,5-tetramethyl-3-imidazoline 3-oxide (HTIO)
Synthetic Communications. 2006. V.36. N19. P.2763-2768. DOI: 10.1080/00397910600767272 WOS Scopus РИНЦ OpenAlex
Improved synthesis of 1-hydroxy-2,2,5,5-tetramethyl-3-imidazoline 3-oxide (HTIO)
Synthetic Communications. 2006. V.36. N19. P.2763-2768. DOI: 10.1080/00397910600767272 WOS Scopus РИНЦ OpenAlex
Dates:
| Published print: | Sep 1, 2006 |
| Published online: | Feb 16, 2007 |
Identifiers:
| Web of science: | WOS:000241196300002 |
| Scopus: | 2-s2.0-33750080441 |
| Elibrary: | 13525753 |
| OpenAlex: | W1986992670 |