Synthesis of 2-alkyl and 2-aryl pyrimidines from beta-chlorovinyl ketones of cyclopentanone type Full article
| Journal |
Synthetic Communications
ISSN: 0039-7911 , E-ISSN: 1532-2432 |
||||
|---|---|---|---|---|---|
| Output data | Year: 2001, Volume: 31, Number: 2, Pages: 233-243 Pages count : DOI: 10.1081/SCC-100000204 | ||||
| Authors |
|
||||
| Affiliations |
|
Abstract:
Amidines react in the presence of NaHCO3 with beta -chlorovinyl ketones, prepared regioselectively by the reaction off 2-acetylcyclopentanone-type diketones with PPh3-CCl4 in 73-78% yield, to afford 2-alkyl (aryl)-pyrimidines annelated with cyclopentane derivatives in 79-87% yields.
Cite:
Popov S.
, Tkachev A.
Synthesis of 2-alkyl and 2-aryl pyrimidines from beta-chlorovinyl ketones of cyclopentanone type
Synthetic Communications. 2001. V.31. N2. P.233-243. DOI: 10.1081/SCC-100000204 WOS Scopus OpenAlex
Synthesis of 2-alkyl and 2-aryl pyrimidines from beta-chlorovinyl ketones of cyclopentanone type
Synthetic Communications. 2001. V.31. N2. P.233-243. DOI: 10.1081/SCC-100000204 WOS Scopus OpenAlex
Dates:
| Published print: | Jan 1, 2001 |
| Published online: | Aug 16, 2006 |
Identifiers:
| Web of science: | WOS:000167384400010 |
| Scopus: | 2-s2.0-0035090788 |
| OpenAlex: | W1964073017 |