SYNTHESIS AND ANTI-INFLAMMATORY ACTIVITY OF TYROSOL AND ITS STRUCTURAL ANALOGS Full article
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Pharmaceutical Chemistry Journal
ISSN: 0091-150X , E-ISSN: 1573-9031 |
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| Output data | Year: 2019, Volume: 52, Number: 11, Pages: 907-911 Pages count : DOI: 10.1007/s11094-019-01924-1 | ||
| Tags | p-tyrosol; hydroxyalkylphenols; anti-inflammatory and antiulcer activity | ||
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Abstract:
The anti-inflammatory activity of tyrosol and 12 structural analogs including 3 new compounds was determined. Several structure-activity (anti-inflammatory) relationships were found. Adding a tert-butyl substituent to the aromatic ring and increasing the length of the alkyl chain decreased the anti-inflammatory activity. Pronounced antiulcer activity was found for p-tyrosol.
Cite:
Krysin A.P.
, Tolstikova T.G.
, Dolgikh M.P.
, Shul'ts E.E.
, Pokrovskii L.M.
SYNTHESIS AND ANTI-INFLAMMATORY ACTIVITY OF TYROSOL AND ITS STRUCTURAL ANALOGS
Pharmaceutical Chemistry Journal. 2019. V.52. N11. P.907-911. DOI: 10.1007/s11094-019-01924-1 WOS Scopus РИНЦ OpenAlex
SYNTHESIS AND ANTI-INFLAMMATORY ACTIVITY OF TYROSOL AND ITS STRUCTURAL ANALOGS
Pharmaceutical Chemistry Journal. 2019. V.52. N11. P.907-911. DOI: 10.1007/s11094-019-01924-1 WOS Scopus РИНЦ OpenAlex
Original:
Крысин А.П.
, Толстикова Т.Г.
, Долгих М.П.
, Шульц Э.Э.
, Покровский Л.М.
Синтез и противовоспалительная активность тирозола и его структурных аналогов
Химико-фармацевтический журнал (PHARM CHEM J+). 2018.
Т.52. №11. С.32-36. DOI: 10.30906/0023-1134-2018-52-11-32-36
РИНЦ
OpenAlex
Синтез и противовоспалительная активность тирозола и его структурных аналогов
Химико-фармацевтический журнал (PHARM CHEM J+). 2018.
Т.52. №11. С.32-36. DOI: 10.30906/0023-1134-2018-52-11-32-36
РИНЦ
OpenAlex
Dates:
| Published print: | Feb 1, 2019 |
| Published online: | Feb 12, 2019 |
Identifiers:
| Web of science: | WOS:000461018000005 |
| Scopus: | 2-s2.0-85061494185 |
| Elibrary: | 38666851 |
| OpenAlex: | W2914511859 |