Polyunsaturated Fatty Acids and Their Correlations with Parameters of Oxidative/Antioxidant Potential of the Blood and Lipoprotein-Associated Phospholipase A2 in Coronary Atherosclerosis Full article
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Bulletin of Experimental Biology and Medicine
ISSN: 0007-4888 |
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| Output data | Year: 2018, Volume: 166, Number: 1, Pages: 11-14 Pages count : DOI: 10.1007/s10517-018-4277-5 | ||||||
| Tags | coronary atherosclerosis; fatty acids; oxidative stress; antioxidant defense; lipoprotein-associated phospholipase A2 | ||||||
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Abstract:
We studied serum content of some polyunsaturated fatty acids and their correlations with parameters of oxidative stress (FORT), antioxidant protection (FORD), lipoprotein-associated phospholipase A2 (LP-PLA2), and serum level of LPO products in male patients with coronary atherosclerosis. The mass fraction of polyunsaturated fatty acids and FORD were lower, while LP-PLA2, FORT, and concentration of LPO products were higher than in the control group (conventionally healthy men). Negative correlations of medium strength of polyunsaturated fatty acids with inflammation markers and oxidative stress were revealed, which can indicate that the decrease in polyunsaturated fatty acids content is associated with enhanced generation of free radicals, and consequently with increased risk of early atherosclerosis development.
Cite:
Shramko V.S.
, Polonskaya Y.V.
, Morozov S.V.
, Chernyak E.I.
, Chernyavsky A.M.
, Ragino Y.I.
Polyunsaturated Fatty Acids and Their Correlations with Parameters of Oxidative/Antioxidant Potential of the Blood and Lipoprotein-Associated Phospholipase A2 in Coronary Atherosclerosis
Bulletin of Experimental Biology and Medicine. 2018. V.166. N1. P.11-14. DOI: 10.1007/s10517-018-4277-5 WOS Scopus РИНЦ OpenAlex
Polyunsaturated Fatty Acids and Their Correlations with Parameters of Oxidative/Antioxidant Potential of the Blood and Lipoprotein-Associated Phospholipase A2 in Coronary Atherosclerosis
Bulletin of Experimental Biology and Medicine. 2018. V.166. N1. P.11-14. DOI: 10.1007/s10517-018-4277-5 WOS Scopus РИНЦ OpenAlex
Original:
Шрамко В.С.
, Полонская Я.В.
, Морозов С.В.
, Черняк Е.И.
, Чернявский А.М.
, Рагино Ю.И.
Полиненасыщенные жирные кислоты и их ассоциации с параметрами окислительно-антиоксидантного потенциала крови и липопротеинассоциированной фосфолипазой a2 при коронарном атеросклерозе
Бюллетень экспериментальной биологии и медицины (B EXP BIOL MED+). 2018. Т.166. №7. С.14-17. РИНЦ
Полиненасыщенные жирные кислоты и их ассоциации с параметрами окислительно-антиоксидантного потенциала крови и липопротеинассоциированной фосфолипазой a2 при коронарном атеросклерозе
Бюллетень экспериментальной биологии и медицины (B EXP BIOL MED+). 2018. Т.166. №7. С.14-17. РИНЦ
Dates:
| Published print: | Nov 1, 2018 |
| Published online: | Nov 12, 2018 |
Identifiers:
| Web of science: | WOS:000452549900003 |
| Scopus: | 2-s2.0-85056384718 |
| Elibrary: | 38623956 |
| OpenAlex: | W2901187578 |