Nitro derivatives of 2,1,3-benzothiadiazole 1-oxides: synthesis, structural study, and NO release Full article
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Russian Chemical Bulletin
ISSN: 1066-5285 , E-ISSN: 1573-9171 |
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| Output data | Year: 2018, Volume: 67, Number: 1, Pages: 95-101 Pages count : DOI: 10.1007/s11172-018-2042-6 | ||||
| Tags | 1,2,5-thiadiazole 1-oxides; sulfur monochloride; ortho-nitroamino derivatives; synthesis; nitric oxide | ||||
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Abstract:
A convenient one-pot synthesis of nitro derivatives of 2,1,3-benzothiadiazole 1-oxides by the reaction of o-nitroanilines with sulfur monochloride was developed. The structural features of 4-nitrobenzothiadiazole and its N-oxide were considered. High in vitro release of nitric oxide (69%) was found for a 6-nitro-2,1,3-benzothiadiazole sample by the Griess assay, which indicated good prospects for this class of compounds.
Cite:
Konstantinova L.S.
, Knyazeva E.A.
, Gatilov Y.V.
, Zlotin S.G.
, Rakitin O.A.
Nitro derivatives of 2,1,3-benzothiadiazole 1-oxides: synthesis, structural study, and NO release
Russian Chemical Bulletin. 2018. V.67. N1. P.95-101. DOI: 10.1007/s11172-018-2042-6 WOS Scopus РИНЦ OpenAlex
Nitro derivatives of 2,1,3-benzothiadiazole 1-oxides: synthesis, structural study, and NO release
Russian Chemical Bulletin. 2018. V.67. N1. P.95-101. DOI: 10.1007/s11172-018-2042-6 WOS Scopus РИНЦ OpenAlex
Original:
Константинова Л.С.
, Князева Е.А.
, Гатилов Ю.В.
, Злотин С.Г.
, Ракитин О.А.
Синтез и исследование структуры нитропроизводных 1-оксидов 2,1,3-бензотиадиазолов и их способности выделять no
Известия Академии наук. Серия химическая.(RUSS CHEM B+). 2018. №1. С.95-101. РИНЦ
Синтез и исследование структуры нитропроизводных 1-оксидов 2,1,3-бензотиадиазолов и их способности выделять no
Известия Академии наук. Серия химическая.(RUSS CHEM B+). 2018. №1. С.95-101. РИНЦ
Dates:
| Published print: | Jan 1, 2018 |
| Published online: | Apr 19, 2018 |
Identifiers:
| Web of science: | WOS:000430480200013 |
| Scopus: | 2-s2.0-85045841618 |
| Elibrary: | 35491511 |
| OpenAlex: | W2799463913 |