Synthesis of fluorine-containing arylacetic acids via the DielsAlder reaction of polyfluorinated cyclohexa-2,4-dienones with acetylenes Full article
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Journal of Fluorine Chemistry
ISSN: 0022-1139 |
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| Output data | Year: 1993, Volume: 62, Number: 2-3, Pages: 243-258 Pages count : DOI: 10.1016/S0022-1139(00)80098-6 | ||
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Abstract:
2,3,4,5,6-Pentafluoro-6-chloro-2,4-cyclohexadien-1-one (I) and 3-(pentafluorophenoxy)-6-chloro-2,4,5,6-tetrafluoro-2,4-cyclohexadien-1-one(II) readily undergo the DielsAlderreaction with aryl- and alkyl-substituted acetylenes giving [2+4]-cycloadducts in goodyield. The latter undergo aromatization by nucleophilic agents under mild conditions toα-chlorophenylacetic acid derivatives containing two or three fluorine atoms in the aromaticring. © 1993.
Cite:
Kobrina L.S.
, Bogachev A.A.
Synthesis of fluorine-containing arylacetic acids via the DielsAlder reaction of polyfluorinated cyclohexa-2,4-dienones with acetylenes
Journal of Fluorine Chemistry. 1993. V.62. N2-3. P.243-258. DOI: 10.1016/S0022-1139(00)80098-6 WOS Scopus OpenAlex
Synthesis of fluorine-containing arylacetic acids via the DielsAlder reaction of polyfluorinated cyclohexa-2,4-dienones with acetylenes
Journal of Fluorine Chemistry. 1993. V.62. N2-3. P.243-258. DOI: 10.1016/S0022-1139(00)80098-6 WOS Scopus OpenAlex
Dates:
| Published print: | Jun 1, 1993 |
Identifiers:
| Web of science: | WOS:A1993LJ05700014 |
| Scopus: | 2-s2.0-0000086127 |
| OpenAlex: | W1997235366 |