Synthesis of pyrimidine and 1,3-bishydroxylamine derivatives from enone Mannich base methiodides Full article
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Heterocyclic Communications
ISSN: 0793-0283 |
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| Output data | Year: 2002, Volume: 8, Number: 3, Pages: 249-254 Pages count : 6 DOI: 10.1515/HC.2002.8.3.249 | ||
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Abstract:
Reaction of the bis(aminomethylated) alkylaromatic ketones with methyl iodide gave the enone Mannich base methiodides. Subsequent reaction with two equivalents of methoxyamine or sodium anti-benzaldoximate resulted in 1,3-bismethoxyamine or dinitrone correspondingly. Partial hydroxylaminolyses of dinitrones led to 5-aroyl-1,3-dihydroxy-2-phenylperhydropyrimidines. Reaction of the enone Mannich base methiodides with cyclic paramagnetic amidine gave nitroxides of imidazopyrimidine series.
Cite:
Khlestkin V.K.
, Tikhonov A.Y.
Synthesis of pyrimidine and 1,3-bishydroxylamine derivatives from enone Mannich base methiodides
Heterocyclic Communications. 2002. V.8. N3. P.249-254. DOI: 10.1515/HC.2002.8.3.249 WOS Scopus РИНЦ OpenAlex
Synthesis of pyrimidine and 1,3-bishydroxylamine derivatives from enone Mannich base methiodides
Heterocyclic Communications. 2002. V.8. N3. P.249-254. DOI: 10.1515/HC.2002.8.3.249 WOS Scopus РИНЦ OpenAlex
Dates:
| Published print: | Jan 1, 2002 |
Identifiers:
| Web of science: | WOS:000177803900007 |
| Scopus: | 2-s2.0-0036025098 |
| Elibrary: | 13406403 |
| OpenAlex: | W2321848035 |