Chemical properties of ylidene derivatives of azines. 2. The methylation of dihydropyrimidinylidenecyanoacetic esters and their anions Научная публикация
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Chemistry of Heterocyclic Compounds
ISSN: 0009-3122 , E-ISSN: 1573-8353 |
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| Вых. Данные | Год: 1984, Том: 20, Номер: 11, Страницы: 1270-1275 Страниц : DOI: 10.1007/BF00505721 | ||
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Реферат:
The methylation of dihydropyrimidinylidenecyanoacetic esters by various methylating reagents leads to better yields when anions of ylidene derivatives of pyrimidine are used. The structure of the products of N- and C-methylation formed and their ratio were established with the aid of the IR and UV spectra and by 1H and 13C NMR spectroscopy. The product of C-methylation contains a methyl group at the C(7) atom of the side chain, while the product of N-methylation contains a methyl group at the nitrogen atom of the pyrimidine ring. For 6-ylidene derivatives, N-methylation occurs at the heterocyclic atom distant from the tautomerizing chain. For 2-and 6-ylidene derivatives of pyrimidine, the ratio of the products of N- and C-methylation can be changed by varying the alkylating reagent. © 1985 Plenum Publishing Corporation.
Библиографическая ссылка:
Zagulyaeva O.A.
, Grigorkina O.A.
, Mamatyuk V.I.
, Mamaev V.P.
Chemical properties of ylidene derivatives of azines. 2. The methylation of dihydropyrimidinylidenecyanoacetic esters and their anions
Chemistry of Heterocyclic Compounds. 1984. V.20. N11. P.1270-1275. DOI: 10.1007/BF00505721 Scopus РИНЦ OpenAlex
Chemical properties of ylidene derivatives of azines. 2. The methylation of dihydropyrimidinylidenecyanoacetic esters and their anions
Chemistry of Heterocyclic Compounds. 1984. V.20. N11. P.1270-1275. DOI: 10.1007/BF00505721 Scopus РИНЦ OpenAlex
Даты:
| Опубликована в печати: | 1 нояб. 1984 г. |
Идентификаторы БД:
| Scopus: | 2-s2.0-34250118843 |
| РИНЦ: | 30986675 |
| OpenAlex: | W2997250268 |