Intramolecular cyclization of 5-amino-4-bis (β-chloroethyl)aminopyrimidines Научная публикация
| Журнал |
Chemistry of Heterocyclic Compounds
ISSN: 0009-3122 , E-ISSN: 1573-8353 |
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| Вых. Данные | Год: 1983, Том: 19, Номер: 10, Страницы: 1120-1127 Страниц : DOI: 10.1007/BF00505771 | ||
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Реферат:
4-R-5,6,7,8,9,10-Hexahydroimidazo [1,2,3-i,j] pteridinium chlorides and 4-R-7-(β-chloroethyl)-7,8-dihydroimidazo[1,2-c]pyrimidinium chlorides were obtained in the reaction of 6-R-5-amino-4-bis(β-hydroxyethyl) aminopyrimidines (R = H, Cl) with SOCl2 or POCl3. The pteridinium chlorides are formed through cyclization of the intermediately formed 4-R-8-(β-chloroethyl)-5,6,7,8-tetrahydropteridines, which, for R = Cl, were obtained independently by reduction of 4-chloro-6-bis-(β-chloroethyl) amino-5-nitropyrimidine. The conditions for the cyclization of imidazopyrimidinium chlorides to give imidazopteridinium chlorides were investigated. © 1984 Plenum Publishing Corporation.
Библиографическая ссылка:
Naumenko I.I.
, Shishkin G.V.
Intramolecular cyclization of 5-amino-4-bis (β-chloroethyl)aminopyrimidines
Chemistry of Heterocyclic Compounds. 1983. V.19. N10. P.1120-1127. DOI: 10.1007/BF00505771 Scopus РИНЦ OpenAlex
Intramolecular cyclization of 5-amino-4-bis (β-chloroethyl)aminopyrimidines
Chemistry of Heterocyclic Compounds. 1983. V.19. N10. P.1120-1127. DOI: 10.1007/BF00505771 Scopus РИНЦ OpenAlex
Даты:
| Опубликована в печати: | 1 окт. 1983 г. |
Идентификаторы БД:
| Scopus: | 2-s2.0-34250139524 |
| РИНЦ: | 30988691 |
| OpenAlex: | W3163573836 |