Tautomerism of azine derivatives. 6. Tautomerism of 2-pyrimidinylmethane derivatives Научная публикация
| Журнал |
Chemistry of Heterocyclic Compounds
ISSN: 0009-3122 , E-ISSN: 1573-8353 |
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| Вых. Данные | Год: 1984, Том: 20, Номер: 6, Страницы: 676-680 Страниц : DOI: 10.1007/BF00508683 | ||
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Реферат:
The existence of a pyrimidinyl-pyrimidinylidene tautomeric equilibrium in solutions of 2-pyrimidinylcyanoacetic acid esters in CDCl3 was observed. Unsymmetrically substituted compounds form two types of ylidene tautomers that differ with respect to the position of the NH proton, the ratio between which is controlled by the substituents in the 4 (6) position. The introduction of both donor and acceptor substituents into the 5 position of the pyrimidine ring increases the amount of the pyrimidine form. The same thing occurs when the polarity of the solvent is decreased. The addition of DMSO or DMF to CDCl3 leads to conversion of the intrachelate ylidene tautomers to unchelated tautomers. Protonation (CF3COOH) shifts the equilibrium to favor the ylidene tautomer that has higher basicity. © 1984 Plenum Publishing Corporation.
Библиографическая ссылка:
Lapachev V.V.
, Zagulyaeva O.A.
, Petrenko O.P.
, Bychkov S.F.
, Mamaev V.P.
Tautomerism of azine derivatives. 6. Tautomerism of 2-pyrimidinylmethane derivatives
Chemistry of Heterocyclic Compounds. 1984. V.20. N6. P.676-680. DOI: 10.1007/BF00508683 Scopus РИНЦ OpenAlex
Tautomerism of azine derivatives. 6. Tautomerism of 2-pyrimidinylmethane derivatives
Chemistry of Heterocyclic Compounds. 1984. V.20. N6. P.676-680. DOI: 10.1007/BF00508683 Scopus РИНЦ OpenAlex
Даты:
| Опубликована в печати: | 1 июн. 1984 г. |
Идентификаторы БД:
| Scopus: | 2-s2.0-34250141330 |
| РИНЦ: | 30845220 |
| OpenAlex: | W2949464764 |