Sciact
  • EN
  • RU

Pyrimidines. 73. Synthesis of acetylpyrimidines Full article

Journal Chemistry of Heterocyclic Compounds
ISSN: 0009-3122 , E-ISSN: 1573-8353
Output data Year: 1981, Volume: 17, Number: 7, Pages: 710-714 Pages count : DOI: 10.1007/BF00506042
Authors Naumenko I. I. , Mikhaleva M. A. , Mamaev V. P.
Affiliations
1 (Scopus) Novosibirsk Institute of Organic Chemistry, Siberian Branch, Academy of Sciences of the USSR, Novosibirsk, 630090, Russian Federation

Abstract: It is shown that the use of benzene as the solvent in the preparation of 2- and 4-acetylpyrimidines from cyanopyrimidines via the Grignard reaction makes this reaction a practical method for the preparation of pyrimidinyl ketones. Preparatively convenient methods for the preparation of 4-acetylpyrimidine from 4-ethylpyrimidine through the α-oximino derivative and 5-acetylpyrimidine from 4,6-dichloro derivatives of pyrimidine are proposed. © 1982 Plenum Publishing Corporation.
Cite: Naumenko I.I. , Mikhaleva M.A. , Mamaev V.P.
Pyrimidines. 73. Synthesis of acetylpyrimidines
Chemistry of Heterocyclic Compounds. 1981. V.17. N7. P.710-714. DOI: 10.1007/BF00506042 Scopus РИНЦ OpenAlex
Dates:
Published print: Jul 1, 1981
Identifiers:
≡ Scopus: 2-s2.0-34250224523
≡ Elibrary: 30992338
≡ OpenAlex: W2950960399
Altmetrics: