Synthesis of Substituted 2-(Thiophen-2-yl)-1H-imidazol-1-ols Full article
| Journal |
Russian Journal of Organic Chemistry
ISSN: 1070-4280 , E-ISSN: 1608-3393 |
||
|---|---|---|---|
| Output data | Year: 2017, Volume: 53, Number: 2, Pages: 236-239 Pages count : 4 DOI: 10.1134/S1070428017020166 | ||
| Authors |
|
||
| Affiliations |
|
Abstract:
Substituted 2-(thiophen-2-yl)-1H-imidazol-1-ols were synthesized by cyclization of the corresponding alpha-thienyl nitrones in alkaline medium. alpha-Thienyl nitrones were obtained by reaction of N-(1-hydroxyimine-1-R-propan-2-yl)hydroxylamines with thiophene-2-carbaldehyde in methanol. At boiling alpha-thienyl nitrones in methanol in the presence of sodium methylate 5-aryl(hetaryl)-2-(thiophen-2-yl)-1H-imidazol-1-ols are formed chemoselectively.
Cite:
Os'kina I.A.
, Tikhonov A.Y.
Synthesis of Substituted 2-(Thiophen-2-yl)-1H-imidazol-1-ols
Russian Journal of Organic Chemistry. 2017. V.53. N2. P.236-239. DOI: 10.1134/S1070428017020166 WOS Scopus РИНЦ OpenAlex
Synthesis of Substituted 2-(Thiophen-2-yl)-1H-imidazol-1-ols
Russian Journal of Organic Chemistry. 2017. V.53. N2. P.236-239. DOI: 10.1134/S1070428017020166 WOS Scopus РИНЦ OpenAlex
Original:
Оськина И.А.
, Тихонов А.Я.
Синтез замещённых 2-(тиофен-2-ил)-1н-имидазол-1-олов
Журнал органической химии (RUSS J ORG CHEM+). 2017. Т.53. №2. С.242-245. РИНЦ
Синтез замещённых 2-(тиофен-2-ил)-1н-имидазол-1-олов
Журнал органической химии (RUSS J ORG CHEM+). 2017. Т.53. №2. С.242-245. РИНЦ
Dates:
| Published print: | Feb 1, 2017 |
| Published online: | Apr 18, 2017 |
Identifiers:
| Web of science: | WOS:000399781000016 |
| Scopus: | 2-s2.0-85017501244 |
| Elibrary: | 29500506 |
| OpenAlex: | W2605665553 |