Synthesis of 1,5,6,7-Tetrahydro-4H- benzimidazol-4-one Derivatives from 2,6-Bis(hydroxyimino)cyclohexan-1-one Full article
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Russian Journal of Organic Chemistry
ISSN: 1070-4280 , E-ISSN: 1608-3393 |
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| Output data | Year: 2017, Volume: 53, Number: 1, Pages: 66-73 Pages count : 8 DOI: 10.1134/S1070428017010122 | ||
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Abstract:
The reaction of 2,6-bis(hydroxyimino)cyclohexan-1-one with aldehydes and ammonia afforded 2-substituted 4-hydroxyimino-4,5,6,7-tetrahydro-1H-benzimidazol-1-ols which were hydrolyzed to 1-hydroxy2- R-1,5,6,7-tetrahydro-4H-benzimidazol-4-ones. The N-hydroxy group in the latter can readily by removed by the action of chloroacetone in the presence of a base (potassium carbonate or triethylamine); as a result, 2-substituted 1,5,6,7-tetrahydro-4H-benzimidazol-4-ones were obtained.
Cite:
Samsonov V.A.
Synthesis of 1,5,6,7-Tetrahydro-4H- benzimidazol-4-one Derivatives from 2,6-Bis(hydroxyimino)cyclohexan-1-one
Russian Journal of Organic Chemistry. 2017. V.53. N1. P.66-73. DOI: 10.1134/S1070428017010122 WOS Scopus РИНЦ OpenAlex
Synthesis of 1,5,6,7-Tetrahydro-4H- benzimidazol-4-one Derivatives from 2,6-Bis(hydroxyimino)cyclohexan-1-one
Russian Journal of Organic Chemistry. 2017. V.53. N1. P.66-73. DOI: 10.1134/S1070428017010122 WOS Scopus РИНЦ OpenAlex
Original:
Самсонов В.А.
Синтез производных 1,5,6,7-тетрагидро- 4н-бензимидазол-4-она на основе 2,6- бис(гидроксиимино)циклогексан-1 -она
Журнал органической химии (RUSS J ORG CHEM+). 2017. Т.53. №1. С.71-77. РИНЦ
Синтез производных 1,5,6,7-тетрагидро- 4н-бензимидазол-4-она на основе 2,6- бис(гидроксиимино)циклогексан-1 -она
Журнал органической химии (RUSS J ORG CHEM+). 2017. Т.53. №1. С.71-77. РИНЦ
Dates:
| Published print: | Jan 1, 2017 |
| Published online: | Mar 8, 2017 |
Identifiers:
| Web of science: | WOS:000396525200012 |
| Scopus: | 2-s2.0-85014865828 |
| Elibrary: | 29488922 |
| OpenAlex: | W2593720562 |