Dihydropyrimidin-2(1H)-one and its analogues as a platform for the design and synthesis of new biologically active compounds Full article
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Russian Chemical Reviews
ISSN: 0036-021X , E-ISSN: 1468-4837 |
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| Output data | Year: 2016, Volume: 85, Number: 10, Pages: 1056-1096 Pages count : 41 DOI: 10.1070/RCR4586 | ||
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Abstract:
The data published mainly over two past decades on various types of biological activity of 5-functionally substituted 3,4-dihydropyrimidin-2-ones and their analogues, 2-thiones and 2-imines, and more complex dihydropyrimidine derivatives are summarized. Apart from medicinal chemistry issues, including structure activity relationships, the pharmacological profiles of the most promising derivatives and the routes for further structural modification of known chemical compounds are discussed in general terms. Examples of potential uses of new compounds in medicine as single pharmaceutical agents and as parts of compositions are given.
Cite:
Shkurko O.P.
, Tolstikova T.G.
, Sedova V.F.
Dihydropyrimidin-2(1H)-one and its analogues as a platform for the design and synthesis of new biologically active compounds
Russian Chemical Reviews. 2016. V.85. N10. P.1056-1096. DOI: 10.1070/RCR4586 WOS Scopus РИНЦ OpenAlex
Dihydropyrimidin-2(1H)-one and its analogues as a platform for the design and synthesis of new biologically active compounds
Russian Chemical Reviews. 2016. V.85. N10. P.1056-1096. DOI: 10.1070/RCR4586 WOS Scopus РИНЦ OpenAlex
Original:
Шкурко О.П.
, Толстикова Т.Г.
, Седова В.Ф.
Дигидропиримидин-2(1h)-он и его аналоги как платформа для конструирования и синтеза новых биологически активных соединений
Успехи химии/Uspekhi Khimii. 2016. Т.85. №10. С.1056-1096. РИНЦ
Дигидропиримидин-2(1h)-он и его аналоги как платформа для конструирования и синтеза новых биологически активных соединений
Успехи химии/Uspekhi Khimii. 2016. Т.85. №10. С.1056-1096. РИНЦ
Dates:
| Published print: | Oct 31, 2016 |
| Published online: | Oct 31, 2016 |
Identifiers:
| Web of science: | WOS:000391302300002 |
| Scopus: | 2-s2.0-84994116092 |
| Elibrary: | 32803212 |
| OpenAlex: | W2471195113 |