Reaction of polyfluorinated chalcones with guanidine Full article
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Russian Journal of Organic Chemistry
ISSN: 1070-4280 , E-ISSN: 1608-3393 |
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| Output data | Year: 2015, Volume: 51, Number: 12, Pages: 1745-1752 Pages count : 8 DOI: 10.1134/S1070428015120143 | ||||
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Abstract:
Reactions of polyfluorinated chalcones with guanidine in the presence of bases are accompanied by elimination of the polyfluorophenyl group. 3-(Pentafluorophenyl)-1-phenylprop-2-en-1-one and its derivatives reacted with guanidine under basic conditions to give 4-phenylpyrimidin-2-amine, polyfluorobenzenes, and Michael adducts, 3-(2-amino-4-phenylpyrimidin-5-yl)-3-(4-R-2,3,5,6-tetrafluorophenyl)-1-phenylpropan-1-ones. 1-(Pentafluorophenyl)-3-phenylprop-2-en-1-one and 1,3-bis(pentafluorophenyl)prop-2-en-1-one were converted into cinnamic acid derivatives whose reaction with guanidine afforded 2-amino-6-aryl-5,6-dihydropyrimidin-4(1H)-ones.
Cite:
Borodina E.A.
, Orlova N.A.
, Gatilov Y.V.
, Sal'nikova O.I.
Reaction of polyfluorinated chalcones with guanidine
Russian Journal of Organic Chemistry. 2015. V.51. N12. P.1745-1752. DOI: 10.1134/S1070428015120143 WOS Scopus РИНЦ OpenAlex
Reaction of polyfluorinated chalcones with guanidine
Russian Journal of Organic Chemistry. 2015. V.51. N12. P.1745-1752. DOI: 10.1134/S1070428015120143 WOS Scopus РИНЦ OpenAlex
Original:
Соболева Е.А.
, Орлова Н.А.
, Гатилов Ю.В.
, Сальникова О.И.
Взаимодействие полифторхалконов с гуанидином
Журнал органической химии (RUSS J ORG CHEM+). 2015. Т.51. №12. С.1778-1785. РИНЦ
Взаимодействие полифторхалконов с гуанидином
Журнал органической химии (RUSS J ORG CHEM+). 2015. Т.51. №12. С.1778-1785. РИНЦ
Dates:
| Published print: | Dec 1, 2015 |
| Published online: | Jan 23, 2016 |
Identifiers:
| Web of science: | WOS:000368737400014 |
| Scopus: | 2-s2.0-84955440241 |
| Elibrary: | 26843243 |
| OpenAlex: | W2340405474 |