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Alkaloids of the Flora of Siberia and Altai. XXI.*5'-(1,2,3-Triazolyl)-Substituted Lappaconitine Derivatives Full article

Journal Chemistry of Natural Compounds
ISSN: 0009-3130 , E-ISSN: 1573-8388
Output data Year: 2015, Volume: 51, Number: 6, Pages: 1142-1146 Pages count : DOI: 10.1007/s10600-015-1511-5
Tags lappaconitine; 1H-1,2,3-triazoles; azides
Authors Romanov V. E. 1,2 , Shul'ts E. E. 1,2
Affiliations
1 (Данные Web of science) Russian Acad Sci, NN Vorozhtsov Novosibirsk Inst Organ Chem, Siberian Branch, Novosibirsk 630090, Russia
2 (Данные Web of science) Novosibirsk State Natl Res Univ, Novosibirsk 630090, Russia

Abstract: New derivatives of the diterpene alkaloid lappaconitine containing a 1H-substituted 1,2,3-triazol-4-yl substituent in the anthranilate C-5 (') -position were synthesized via the reaction of 5 (') -ethynyllappaconitine with aromatic or aliphatic azides in the presence of aqueous CuSO4 and sodium ascorbate in DMF. The yields of the 1,4-disubstituted 1,2,3-triazoles were 40-73% and depended on the nature of the azide.
Cite: Romanov V.E. , Shul'ts E.E.
Alkaloids of the Flora of Siberia and Altai. XXI.*5'-(1,2,3-Triazolyl)-Substituted Lappaconitine Derivatives
Chemistry of Natural Compounds. 2015. V.51. N6. P.1142-1146. DOI: 10.1007/s10600-015-1511-5 WOS Scopus РИНЦ OpenAlex
Dates:
Published print: Nov 1, 2015
Published online: Nov 11, 2015
Identifiers:
Web of science: WOS:000365190200029
Scopus: 2-s2.0-84957580365
Elibrary: 26954788
OpenAlex: W2243489494
Citing:
DB Citing
Web of science 2
Scopus 2
Elibrary 3
OpenAlex 2
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