Synthesis and cytotoxic activity of substituted hexahydro-2H-4,6-(epoxymethano)chromen-8(5H)-ones obtained from (-)-verbenone Full article
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Russian Chemical Bulletin
ISSN: 1066-5285 , E-ISSN: 1573-9171 |
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| Output data | Year: 2015, Volume: 64, Number: 9, Pages: 2257-2260 Pages count : DOI: 10.1007/s11172-015-1148-3 | ||||
| Tags | monoterpene; cytotoxicity; verbenone; clay; heterocyclic compounds | ||||
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Abstract:
A number of compounds with a substituted hexahydro-2H-4,6-(epoxymethano)chromen-8(5H)-one framework was synthesized starting from monoterpenoid (-)-verbenone and aromatic aldehydes containing methoxy and hydroxy groups. Cytotoxic activity of these compounds on human tumor cell lines was studied for the first time. Compounds containing three methoxy groups in each aromatic ring were found to be the most promising for further studies.
Cite:
Il'ina I.V.
, Pokrovsky M.A.
, Mikhalchenko O.S.
, Korchagina D.V.
, Volcho K.P.
, Pokrovsky A.G.
, Salakhutdinov N.F.
Synthesis and cytotoxic activity of substituted hexahydro-2H-4,6-(epoxymethano)chromen-8(5H)-ones obtained from (-)-verbenone
Russian Chemical Bulletin. 2015. V.64. N9. P.2257-2260. DOI: 10.1007/s11172-015-1148-3 WOS Scopus РИНЦ OpenAlex
Synthesis and cytotoxic activity of substituted hexahydro-2H-4,6-(epoxymethano)chromen-8(5H)-ones obtained from (-)-verbenone
Russian Chemical Bulletin. 2015. V.64. N9. P.2257-2260. DOI: 10.1007/s11172-015-1148-3 WOS Scopus РИНЦ OpenAlex
Original:
Ильина И.В.
, Покровский М.А.
, Патрушева О.С.
, Корчагина Д.В.
, Волчо К.П.
, Покровский А.Г.
, Салахутдинов Н.Ф.
Синтез и цитотоксическая активность замещенных гексагидро-2 н-4,6-(эпоксиметано)хромен-8(5 н)-онов, получаемых из (-)-вербенона
Известия Академии наук. Серия химическая.(RUSS CHEM B+). 2015. №9. С.2257. РИНЦ
Синтез и цитотоксическая активность замещенных гексагидро-2 н-4,6-(эпоксиметано)хромен-8(5 н)-онов, получаемых из (-)-вербенона
Известия Академии наук. Серия химическая.(RUSS CHEM B+). 2015. №9. С.2257. РИНЦ
Dates:
| Published print: | Sep 1, 2015 |
| Published online: | Sep 27, 2016 |
Identifiers:
| Web of science: | WOS:000383958300038 |
| Scopus: | 2-s2.0-84988719637 |
| Elibrary: | 27567848 |
| OpenAlex: | W2525390355 |